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Drug repurposing is using a drug previously approved for one condition to treat an entirely different condition (like cancer). In cancer care, repurposed drugs are usually gentler than FDA-approved cancer treatments. They include common drugs for diabetes, high blood pressure, infections, and more. Tina & Leah talk about who should consider this strategy and some of the most commonly used repurposed drugs.
Repurposing Drugs in Oncology- ReDo Project link
The Anticancer Fund
Care Oncology Clinic (we have no affiliation!) - good info & access to repurposed drugs
Thorough review of mechanisms for repurposed drugs in cancer
Cimetidine- early study suggesting benefit in colorectal cancer
Review of cimetidine in colorectal cancer
Review of better blood sugar regulation leading to better outcomes in cancer care
Metformin- early study suggesting benefit in ovarian cancer
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00:00 - Pandemic ripples... for better or worse.
04:27 - What are Repurposed drugs?
05:57 - Cimetidine (Tagamet)
07:37 - Metformin
10:10 - Blood sugar and outcomes
12:45 - Aspirin
18:50 - The big picture (Metro Map?)
24:21 - Blood pressure drugs
28:58 - Doxycycline
30:56 - Statin drugs
33:39 - Anti Parasitic drugs (Mebendazole, Ivermectin)
43:42 - The bigger picture
48:00 - Wrap up
