March 26, 2025

Young Adults and Cancer: The Truth About Rising Rates and Prevention

Young Adults and Cancer: The Truth About Rising Rates and Prevention
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Season 4

The diagnosis of cancer is rising in young adults (<45 years old). This episode of The Cancer Pod delves into potential reasons behind this trend, including epigenetics, environmental exposures, microbiome differences, and lifestyle factors. Tina and Leah discuss the types of cancers most commonly seen in younger adults, symptoms to watch for, and the significance of advocating for timely and accurate diagnoses. And, get ready for the next episode on cancer fakes and frauds! 

Links we mention in this episode:

Cancer rates are 2-3 times higher today than two generations ago

Heavy metals (lead, cadmium, arsenic, etc.) in tattoos as a possible contributor

Why diagnosis of cancer is often delayed in young adults

Types of cancers more common in young adults

Young adults with colorectal cancer have better outcomes than older adults

The increasing rate of colorectal cancer in young adults worldwide

The SHIELD blood test for colorectal cancer

Support the show

Our website: https://www.thecancerpod.com

Become a member of The Cancer Pod Community! Gain access to live events, exclusive content, and so much more. Join us today and be part of the journey!

Email us: thecancerpod@gmail.com

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THANK YOU for listening!

Chapters

02:36 - Membership is Open!

03:07 - Intro

10:38 - Why is cancer on the rise in young adults?

11:00 - Genetics and Epigenetics

15:23 - Pollutants, Chemicals/Carcinogens

22:22 - Microbiome and Oncobiome

30:12 - Diet and Nutrition

31:29 - Movement and Exercise

34:46 - Sleep (and Light at Night, LAN)

37:32 - Is it COVID? COVID vaccines?

41:25 - What cancers are on the rise in young adults?

42:30 - What symptoms signal possible cancers?

43:28 - Considerations for those who are diagnosed as young adults

46:06 - How to reduce your risk of cancer

47:24 - The films to watch for our next episode on Fakes and Frauds

49:15 - Wrap up

Transcript
WEBVTT

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Tina,

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Leia.

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it's kind of exciting.

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We have a membership now.

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I would love to get to know some folks who are listening to us.

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Yeah.

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So if somebody wants to join us in our membership in our cancer pod community, they can head over to our website and

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Don't we become a pod of our own, like a pod of people?

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we become a pod, which kind of makes me think of evasion of body snatchers, but, um, but anyway, um, yeah, head over to our website and you click on buy me a coffee, and if you want, you can just buy us a coffee, a one-time deal, or you can join our membership.

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We have three levels to choose from, and each one offers different bonus content and exclusive benefits.

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Yeah.

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And we can keep on doing what we're doing.

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Make it a podcast Since September, 2021.

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so today we're gonna be talking about.

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It's been in the news about young people, younger people getting cancer.

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Um, are younger people getting more cancer?

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Are younger people getting cancers that are typically not common for people their age?

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So

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Mm-hmm.

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And is this a phenomenon that is unique to the United States or is it more of a global issue?

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So we'll talk about that and more

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stick around.

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I'm Dr.

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Tina Kayser, and as Leia likes to say, I'm the science y one.

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And I'm Dr.

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Leia Sherman, and I'm the cancer insider.

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And we're two naturopathic doctors who practice integrative cancer care.

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But we're not your doctors.

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This is for education, entertainment, and informational purposes only.

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Do not apply any of this information without first speaking to your doctor.

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The views and opinions expressed on this podcast by the hosts and their guests are solely their own.

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Welcome to the Cancer Pod.

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Hi Tina.

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Hello Leah?

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today we're talking about young adults and cancer,

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Yes.

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Is the incidents on the rise and, uh, if so, why?

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right?

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there are a lot of different theories out there.

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we have our own views yeah, so when they talk about younger people, it is typically people under, 45, I guess, is kind of what they're looking at.

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it's interesting because the study that I saw.

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Looked at two different groups.

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It looked at millennials and boomers, which is, you know, being a member of Gen X, feeling a little left out, especially because there are higher cancer incidence rates in Gen X as well.

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But they're looking at millennials and so that's people who are born between 1981 and 1996.

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however old that makes them.

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Dang it, my math is bad.

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The youngest millennials will turn 30 in 2026.

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Really?

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Yes.

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You're getting old.

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Oh my god.

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All right, so there are some cancers.

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I mean, I guess every cancer kind of has, its typical age range.

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And what's really unusual is that there are cancers that are more associated with older people.

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People over the age of 50, that younger people are getting things like pancreatic cancer, renal cancer.

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You know, I just wanna put out there, this is not, I wanna say something right here at the beginning age.

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And the aging process is a risk factor for cancer.

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So you can't stop that one.

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There's only one way to stop aging, and that's not a good's not a good option,

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It's not recommended.

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right?

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So I'm saying that because right outta the gates, even when we say these are higher in younger people, it still is not near the rates of what people get after the age of say, 60, 65.

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We're talking about a different, it's higher in the age group, but it doesn't come close to what people are getting as they age.

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'cause aging itself is a risk factor that we can't do anything about other than not age anymore, which means that you're not here.

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So I'm saying that outta the gates.

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'cause I just wanna be very clear that even when we say the incidence is higher, it's still a very low incidence in a, in a global sense.

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Like when you're looking at the numbers compared to higher, ages.

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And I think in, like in my work experience working at CTCA, I saw a lot of younger people who had breast cancer, colon cancer, you know, ovarian cancer, just more unusual, I don't wanna say unusual cancers, but I saw a lot of younger people because that's where people went.

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Yes.

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Yes.

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That's where they would travel to because of whatever care they were or were not getting where they came from because maybe they weren't diagnosed in a timely manner.

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Whatever happened then they would go to CTCA.

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When I went to Indiana the patient population was so much older and I think that is typical,

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Mm-hmm.

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for the most part.

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So anyways, that's just an aside.

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But yeah, so.

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Can I say one more thing on a scale of aging?

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Even when we talk about young cancers, we're not talking about pediatric.

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So pediatric is under 18 years old, so that's a separate category and a separate discussion.

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We're really looking at young adults, which is, you know, like we said, really under 50.

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So round numbers is 20 to 50, and as you age within the 20 to 50 range, the risk does go up because aging is in there.

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That risk factor is still there, even.

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When you are considered a young adult with cancer.

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So that's all.

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I just wanna be very clear about the population we're talking about.

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and I don't know where I saw it in my research for this, but, um, early onset breast cancer is considered younger than 45, and colorectal is considered younger than 50.

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Mm-hmm.

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And I do remember a long time ago, um, I.

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I was a big fan of the Today Show, and I used to watch, Katie Couric her husband was diagnosed with colon cancer and he was in his forties and that was really unusual at the time.

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he passed away and it was just, the whole thing was just really, I remember like, I wasn't working in, medicine, I was working in graphic design at the time, and I just remember just, it was just, it was all really surprising because it was so unusual.

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you know, now we hear about, I mean, not only people who follow us on.

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Our, social media, but you know, celebrities, um, Chadwick, Bozeman,

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Hmm.

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um, James VanDerBeek.

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You know, these are young people who, were diagnosed at a young age.

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Yeah.

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And when we're talking about colorectal cancer, just like people over 50, people under 50 need to be screened.

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And if we can find that cancer at earlier stages, the outcomes are much, much better than finding it at a later stage of disease.

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in the grand scheme, bright sided to all of this, when you compare a people over 15, people under 50 with colorectal cancer, specifically, people who are younger do have better outcomes.

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They have less recurrence, they live longer.

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there's been studies that have compared, um, young adults with colorectal cancer from people who are over the age of 50.

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the outcomes are generally better.

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Now, I don't know if that's due to more aggressive treatment or just healthier because you're younger and you have more resilience built in.

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it doesn't matter.

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But on the bright side, um, it does have a better prognosis.

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If it's diagnosed.

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And I mean, that's one good thing about the, the guidelines for colonoscopies being changed, and now it's 45,

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Mm-hmm.

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where it used to be 50 to get your colonoscopy unless you had a family history.

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That was for Caucasians.

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It has been 45 for African Americans for a while.

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Okay.

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but yeah, so if you had a family history, then it would be based on the age that, your relative was, diagnosed, But, am finding, and maybe this is just again, you know, because we have a certain population who follows us on social media, it's not always diagnosed in a timely manner when you are younger than 45 because it's being dismissed as you have IBS you have hemorrhoids,

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Yes.

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Al and I think it's the same with breast cancer.

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I mean, I don't know how many young patients I had who were diagnosed with breast cancer, under 30, who were told, oh, it's not breast cancer.

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You're too young to have cancer.

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Honestly, that's where all those numbers that I'm talking about work against you as an individual.

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So you're an individual showing up at your doctor with whatever symptomology, x, y, Z symptoms.

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And that doctor is playing percentages in their head, like, what's the likelihood that this is benign?

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What's the likelihood that this is cancer?

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So they're gonna probably not diagnose it right out of the gates.

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So your, your age works against you in some ways in finding it early.

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Yeah.

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And I, I think that's a lot of the times the case.

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One bright spot there is for colorectal cancer, in July of 2024, the FDA approved a new test, a blood test for colorectal cancer that is just a blood draw.

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So in some ways it's easier to get.

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That done.

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and get your doctor to agree to just, can you just put that on my, on my lab or if you live in a state that allows it, you can order it yourself.

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depends what state you live in, in the nation.

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'cause healthcare in the United States is state by state.

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There are stool tests for colorectal cancer that can be done, but this is a blood test, so I feel like adoption will be faster than it was for stool testing, which is the Cologuard commercial with that little blue box that smiles and, yeah, it's the same company.

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This is called shield.

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The name of the test is, is called Shield.

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Okay.

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And we could put a link to that in our show notes.

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Yeah.

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So, okay.

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So there are, five or six theories, as to why younger people are getting cancer or that they're being diagnosed with cancer.

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Um, and the first one is epigenetics,

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Epigenetics?

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which is different than genetics.

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So there is that, I guess we should start with that.

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So what is it like five to 10% of all people who are diagnosed with cancer?

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It's actually genetic.

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Mm-hmm.

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I think we're gonna find out.

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It's depending on which type of cancer, I think it's gonna be when we finally find multi genes that put together, like if you have these three or five or 17 genes, do you have a high risk?

00:11:21.389 --> 00:11:31.470
We're getting there with that kind of data for single genes, like one gene, like the BRCA gene, BRCA mutation, or deletion So when it's a single gene, I would say it's gonna be 10% or so.

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Okay, so we're not gonna talk about that.

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We're not gonna talk about the, the genetic component.

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we did tackle genetic cancers once upon a time.

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It's in our catalog back in 2021 or 2022.

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yeah.

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So again, we'll, we'll link to that.

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okay, so then the other word I said epigenetics.

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What, what are epigenetics, Tina?

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Epi.

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Literally means above.

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So above the gene.

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So this is ways that our genes are turned on or off.

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So epigenetics has to do with regulation of the gene.

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And epigenes is very consequential.

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It is highly responsive to its environment.

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So for example, with epigenetics, you can unmask, meaning you begin to express a gene that's been silenced for generations and generations.

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But if your environment, literally your environment where the DNA is literally the cellular environment, what it's in needs, that gene it over time says, oh, we have reason to unmask this gene.

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Let's go ahead and do it.

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It will then uncover a gene that's been silenced.

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It's been sitting there, but it just hasn't done anything until you provoke it.

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And so we change our epigenetics more.

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Readily than the actual gene itself, which is made up of ATT c and g.

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You know that little spiral that we all think of A DNA looks like, right?

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It

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All the way back to, to, you know, biology class.

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Yeah.

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The helix, the double helix of DNA, that's a whole nother story, but the double helix of the DNA is att C and g and that does not change as readily.

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That's very difficult changing that the epigenetics is more fluid and changes generation to generation.

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So if my my great grandfather was a chimney sweep.

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that might have consequences on my epigenetics today because his body had to uncover genes to deal with the soot.

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Does that make sense?

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Mm-hmm.

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Yeah.

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So your parents or grandparents' exposures, they have an influence on your epigenetics.

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Yes, and it's generational, so it's very slow and hard to track.

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I think we are seeing some epigenetic results of what our grandparents and even our great grandparents saw when we had pesticides like DDT that were pervasive.

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Everybody was exposed to them.

00:13:45.097 --> 00:13:53.533
Oh yeah, because we've, all heard stories about people running after the, the mosquito spring, the fogger, the truck that had the fog coming out the back.

00:13:53.832 --> 00:14:01.052
yeah, I remember like the planes going over, spraying pesticides, over certain areas in places where I've lived so.

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Yeah.

00:14:02.192 --> 00:14:07.809
And the idea that the epigenetics is consequential, has been proven in animals again and again.

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So there's no, there's no dearth of information on this.

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There's plenty of information showing that, you know, it is not your parents, but your grandparents and even their, their parents that gets handed down.

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I think the most acute phase when this is happening is during pregnancy.

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I think that's a time that we have to really think about how things are being handed down because When someone's pregnant, when the ovaries in the fetus are forming, there could be consequences, right?

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Then that is when the genetics of that baby's children and whenever that baby goes on to have children.

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Those ovaries are already set.

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The stage is set for your ovaries in utero when you're a fetus.

00:14:47.029 --> 00:14:48.049
For men, it's different.

00:14:48.289 --> 00:14:49.909
Sperm comes and goes.

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Sperm generation is not set when you're a fetus.

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Sperm generation is now.

00:14:56.919 --> 00:15:07.759
And so I mean, that person should really be very, very, very conscious of no drugs, no alcohol, no, no chemicals, no pesticides, eat like super duper cleanly, all that kind of stuff.

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They have to live in a bubble.

00:15:09.679 --> 00:15:11.105
They basically have to live in a bubble.

00:15:11.495 --> 00:15:13.913
Well, you have to be conscientious, I think.

00:15:14.092 --> 00:15:14.634
I think that we can all.

00:15:14.952 --> 00:15:15.702
Do our best.

00:15:15.702 --> 00:15:20.143
It's impossible to be, you know, where we were before the industrial age.

00:15:20.383 --> 00:15:24.503
That's not gonna happen because even our air, in every city is, is not what it used to be.

00:15:24.653 --> 00:15:24.982
So,

00:15:25.330 --> 00:15:30.879
Well, that can lead us to the another one, which is environmental exposures, right?

00:15:30.879 --> 00:15:35.409
So epigenetics and environmental exposures, they're very intertwined.

00:15:35.899 --> 00:15:36.590
absolutely.

00:15:37.009 --> 00:15:37.429
Yeah.

00:15:37.850 --> 00:15:39.799
And we have discussed this before.

00:15:39.799 --> 00:15:44.809
we talked about microplastics, we talked about forever, chemicals in different episodes.

00:15:45.090 --> 00:15:46.139
all of those.

00:15:46.679 --> 00:15:56.230
Play a part, yeah, I mean, once you become conscious of it, it's almost, I, it's, so for me it's very stress inducing because it's like every, there, there's just plastic everywhere.

00:15:56.799 --> 00:15:57.610
Everywhere.

00:15:58.148 --> 00:16:01.113
I feel like when you start looking at clothing, you really start to go, oh.

00:16:01.330 --> 00:16:01.750
right.

00:16:01.750 --> 00:16:08.019
With all the microfiber, the, um, sportswear, endurance, wear, hiking stuff, all of that.

00:16:08.080 --> 00:16:08.409
Yeah.

00:16:08.409 --> 00:16:12.385
We're, we're trying to shift more to products made from wool.

00:16:12.775 --> 00:16:14.905
but it's, it's hard.

00:16:14.905 --> 00:16:20.035
I mean, you look at your sneakers, you look at everything, you're hiking shoes, it's, it's just kind of everywhere.

00:16:20.456 --> 00:16:27.413
you look in your kitchen and it's just, it's shocking how much plastic, we have in our refrigerator and Yeah.

00:16:27.413 --> 00:16:28.403
In your grocery cart.

00:16:28.403 --> 00:16:30.337
Yeah, I'm a fan of the old school, right?

00:16:30.337 --> 00:16:31.327
Like, just go backwards.

00:16:31.327 --> 00:16:34.842
You use glass, use ball, jars, glass is usually inert.

00:16:34.842 --> 00:16:43.416
But when you buy something, when you buy, like things from a deli counter, you know, cheese or whatever, they'll ask, do you want us to wrap it in paper or plastic?

00:16:43.416 --> 00:16:44.436
And we're always like, paper.

00:16:44.855 --> 00:16:46.596
but not, not everyone has that.

00:16:46.836 --> 00:16:53.355
Um, so if you buy packaged cheese, it comes in plastic and then you go home, you take it outta the plastic and you put it in class.

00:16:53.355 --> 00:16:56.296
But it's already been, it's already been in plastic.

00:16:56.566 --> 00:17:01.066
It's, um, and I don't wanna go too much into this because we have talked about microplastics before.

00:17:01.816 --> 00:17:02.176
Yeah.

00:17:02.505 --> 00:17:04.276
And they, they do disturb the gut.

00:17:04.472 --> 00:17:04.923
Right?

00:17:05.012 --> 00:17:10.563
And they're found, I mean, they, they, they've been found in, throughout us, like in our, you know, our bodies.

00:17:10.593 --> 00:17:11.073
Um,

00:17:11.492 --> 00:17:13.367
Even in the sacred space of the brain.

00:17:13.545 --> 00:17:14.954
yeah, they've been found in the brain.

00:17:14.954 --> 00:17:17.825
They've been found in testicular tissue.

00:17:18.022 --> 00:17:21.772
If they can pass the blood-brain barrier, yeah, they can go anywhere.

00:17:21.938 --> 00:17:22.387
Yeah.

00:17:22.522 --> 00:17:23.123
ultimately,

00:17:23.173 --> 00:17:23.383
Yeah.

00:17:23.383 --> 00:17:25.893
And, but there are other environmental exposures too.

00:17:25.893 --> 00:17:32.653
you know, the forever chemicals are what we think of, like with the Teflon pan, when Teflon pan came out, those were just such a godsend.

00:17:32.653 --> 00:17:35.173
Everybody used Teflon pan and then they'd get scraped.

00:17:35.173 --> 00:17:40.445
And I remember'cause you're using the wrong utensils, and so then they get scraped and all that Teflon comes up.

00:17:40.685 --> 00:17:41.826
That is so bad for you.

00:17:42.496 --> 00:17:43.006
Yeah.

00:17:43.066 --> 00:17:43.395
Yeah.

00:17:43.395 --> 00:17:44.415
And it's not so inert.

00:17:44.445 --> 00:17:49.759
I mean, if you're cooking over about 400 degrees, which is not difficult, then it starts to degrade whether it's scratched or not.

00:17:49.819 --> 00:17:53.180
So there are better alternatives now to that.

00:17:53.480 --> 00:17:59.420
it's really hard to track environmentally because we live in a soup, right, of so many different exposures.

00:17:59.750 --> 00:18:03.710
Our soil, our air quality, sometimes the water quality.

00:18:03.799 --> 00:18:09.740
So it's really a, it's not an easy one to track back and say, oh, you know, that exposure or that exposure.

00:18:09.965 --> 00:18:17.286
Every time we find one that's really focused upon like DDT or dioxin, we do our best to, you know, regulate that.

00:18:17.286 --> 00:18:22.875
But there is no, like you said, it's, a challenging one'cause there's nowhere that you can completely escape it.

00:18:23.101 --> 00:18:23.490
No.

00:18:23.490 --> 00:18:30.085
And we have our, our cabin up in northern Wisconsin, and we have a septic tank.

00:18:30.565 --> 00:18:33.444
And when they come and empty that septic tank.

00:18:33.792 --> 00:18:40.292
Is everything that we use within the house and you know, the cleaners and everything that we put in there, everything is just very clean and natural.

00:18:40.563 --> 00:18:49.353
But I take medicine, I'm taking Tamoxifen, and so that is in that waste, and they will take that waste and they will spray it on fields.

00:18:49.413 --> 00:18:55.952
And the fields aren't necessarily growing food for humans, but it's out there.

00:18:55.982 --> 00:19:15.779
So, and you know, fortunately we don't take a ton of medications and so it's not, you know, this whole pharmaceutical soup that's in there, but like the thought that they're doing this from multiple homes and they're spraying fields and then the runoff will go into the river and the river goes, you know, down into wherever you know it just.

00:19:15.779 --> 00:19:16.859
That's crazy.

00:19:16.859 --> 00:19:24.609
Like, isn't that crazy that they're spraying human waste and what, like, that's not even the grossest part.

00:19:25.964 --> 00:19:29.170
Like, like it's everything that you put in there.

00:19:29.500 --> 00:19:32.710
And so they're finding, you know, they're, you know, p FFAs and stuff in there too.

00:19:32.710 --> 00:19:36.596
So, and then they're not P FFAs, P FFAs.

00:19:36.776 --> 00:19:37.736
Am I saying that right?

00:19:38.111 --> 00:19:40.316
But you gotta tell folks what that means.

00:19:40.465 --> 00:19:41.756
Well, those are forever chemicals.

00:19:41.756 --> 00:19:43.465
I'm not gonna break down what it, it's a

00:19:43.615 --> 00:19:44.066
Well, yeah.

00:19:44.965 --> 00:19:45.266
Yeah.

00:19:45.296 --> 00:19:45.746
No, yeah.

00:19:45.746 --> 00:19:47.905
You don't have to say the word when you say P Fs, I don't.

00:19:47.935 --> 00:19:48.895
I think you lost people.

00:19:48.895 --> 00:19:49.046
That's

00:19:49.046 --> 00:19:49.586
Oh, okay.

00:19:49.705 --> 00:19:50.695
Well, forever chemicals.

00:19:50.726 --> 00:19:51.296
Forever chemicals.

00:19:51.415 --> 00:20:01.165
And then of course, the thing that I brought up in previous episodes is I went to art school in the eighties and there was a lot of exposure to the solvents.

00:20:01.195 --> 00:20:07.645
Um, the coloring in oil paints that we would get on our hands, then clean it with solvents.

00:20:07.976 --> 00:20:10.736
We just like, we didn't care, you know?

00:20:11.096 --> 00:20:12.266
And so all of that.

00:20:12.566 --> 00:20:14.425
Well, and I think a lot of folks still do that.

00:20:14.455 --> 00:20:16.165
Like they, they'll, I've seen it.

00:20:16.375 --> 00:20:20.455
People paint or they're doing work or they're like, I don't know.

00:20:20.576 --> 00:20:26.202
All sorts of people don't take the precautions'cause they think, oh, it's just gonna be, I do this all the time, or it doesn't hurt.

00:20:26.303 --> 00:20:27.053
Right.

00:20:27.053 --> 00:20:33.923
Or I remember, um, like in photo lab, you know, we'd be in the dark room and we're just like pulling them out.

00:20:33.952 --> 00:20:35.932
You have little tongs, but you're just like, whatever.

00:20:35.932 --> 00:20:42.982
And you just grab it with your hand, you know, it's, you're 18-year-old thing and your photography professor is doing the same thing.

00:20:43.163 --> 00:20:48.323
So, so there're just like so many different ways that we are being exposed to things.

00:20:48.968 --> 00:21:02.498
So back to the young adults with cancer, one of the things that we don't talk about, we we're talking about microplastics now, but there's also a lot of dyes in the, in these plastics, and there's been heavy metals used to make the plastics pretty colors.

00:21:03.067 --> 00:21:07.307
And so even in playgrounds, Playgrounds used arsenic in the wood.

00:21:07.698 --> 00:21:08.478
That wasn't good.

00:21:08.988 --> 00:21:12.778
They got that out and they started using plastics, and the plastics had, heavy metals in it.

00:21:13.198 --> 00:21:21.028
So there's, there's a lot of exposures that we've introduced because we don't have a system that makes sure something is safe.

00:21:21.028 --> 00:21:25.317
We have a system that double checks to see if it's toxic, and if so, at what amount?

00:21:25.887 --> 00:21:26.758
If we check it at all.

00:21:27.292 --> 00:21:29.607
Even, um, tattoos

00:21:29.903 --> 00:21:30.123
Mm.

00:21:30.127 --> 00:21:31.288
Mm-hmm.

00:21:31.428 --> 00:21:38.887
and, you know, speaking as a tattooed person, you know, there are various heavy metals but depending on when you were.

00:21:39.218 --> 00:21:40.117
Tattooed.

00:21:40.117 --> 00:21:42.998
I don't know if they're making them healthier now.

00:21:43.807 --> 00:21:44.827
I have no idea.

00:21:45.038 --> 00:21:52.307
But, um, the tattoo ink, you know, different pigments that are used they have various heavy metals.

00:21:52.827 --> 00:21:58.714
and then that process itself, the inflammation that keeps your tattoo where it is

00:21:59.299 --> 00:21:59.660
Yeah.

00:21:59.660 --> 00:22:00.890
And you know what's interesting about this?

00:22:00.890 --> 00:22:03.045
When we talk about heavy metals, you could argue those are natural.

00:22:03.045 --> 00:22:05.625
Because arsenic occurs in nature, as does lead

00:22:06.194 --> 00:22:06.765
cadmium,

00:22:06.944 --> 00:22:07.424
academy.

00:22:07.694 --> 00:22:11.954
They're all, these aren't synthetic chemicals we're talking about when we say this.

00:22:11.954 --> 00:22:12.704
So I just wanna say that.

00:22:12.704 --> 00:22:16.394
'cause you know, not everything natural is, uh, is okay in any dose either.

00:22:16.394 --> 00:22:20.025
So this is an example where it actually is not good,

00:22:20.210 --> 00:22:20.500
Okay.

00:22:20.595 --> 00:22:25.325
So, We've talked about epigenetics, we talked about environmental exposures.

00:22:25.550 --> 00:22:36.214
There is also, our internal environment, our microbiome that also has been implicated in a possible cause for younger people getting cancer.

00:22:36.910 --> 00:22:43.214
am very much into not just the microbiome of the gut, which we have a lot of information about.

00:22:43.305 --> 00:22:49.464
And we do have a lot of, indications that the bacteria that inhabit the colon.

00:22:49.765 --> 00:22:53.365
Or the breast ducts or the prostate.

00:22:53.875 --> 00:22:59.035
Those organisms when there's cancer are different than when someone does not have cancer.

00:22:59.035 --> 00:23:04.798
They have studies where they, they remove the colorectal cancer and then they look at the bacteria that are near the tumor.

00:23:04.820 --> 00:23:10.431
so the tumor has some bacterial populations that they name and then they look adjacent to it.

00:23:10.461 --> 00:23:11.601
same person, right?

00:23:11.871 --> 00:23:13.431
Same day, same surgery.

00:23:13.881 --> 00:23:18.500
The normal tissue next to the cancerous tissue has different bacteria in it.

00:23:19.101 --> 00:23:30.770
And so I think it's really young as a, as a discipline, like to figure out how the bacteria, and there's other organisms, there's viral particles, there's bacteriophages, which are a type of virus.

00:23:31.131 --> 00:23:32.451
There's yeast in other fungus.

00:23:32.570 --> 00:23:41.611
So there's a, there's a whole community ecology everywhere that there's bacteria, uh, that we say bacteria because it's the dominant population and there's more of that than anything else.

00:23:41.851 --> 00:23:44.941
But the others may not be minor players.

00:23:44.941 --> 00:23:46.530
They could be big players in some of the cancers.

00:23:46.530 --> 00:23:47.010
We don't know.

00:23:47.881 --> 00:23:52.441
So I, I think I'm way into the microbiome, not just with gut, but of the actual cancer.

00:23:52.490 --> 00:23:55.040
I'm trying to get the word onco biome to, to take hold.

00:23:55.490 --> 00:23:57.951
You know, if you look for onco biome right now, you're not gonna see much.

00:23:58.010 --> 00:24:04.250
But I think it's the apt term for when the bacterial communities are actually inside the tumor.

00:24:04.701 --> 00:24:09.290
They're in the cancer, which is heresy 20 years ago.

00:24:09.381 --> 00:24:10.911
That's like, nah.

00:24:11.270 --> 00:24:14.661
All inner organs with the body are sterile.

00:24:15.185 --> 00:24:21.935
They're not, we now know that there are actual bacteria inside certainly inside the tumors.

00:24:22.355 --> 00:24:28.476
And so not only are they there at the primary tumor, but they're there when you look at the metastasis of a tumor too.

00:24:28.476 --> 00:24:32.465
So a colorectal cancer, you can look at the tumor, look inside it, you'll see certain bacteria.

00:24:32.826 --> 00:24:37.086
There's one called Fusobacterium, nucleotum that's really implicated.

00:24:37.415 --> 00:24:39.576
Um, totally normal to have that in your mouth.

00:24:39.665 --> 00:24:41.496
You're not supposed to have it in your colon.

00:24:41.675 --> 00:24:47.819
So it's like, I always think of like ivy or Kudzu, you know, like it's totally normal plants somewhere else.

00:24:47.869 --> 00:24:50.779
That's what I think of with these bacteria and cancers like that Fuso.

00:24:50.779 --> 00:24:51.170
Bacterium.

00:24:51.170 --> 00:25:04.710
Nucleo is totally normal in your saliva and no problem there, but when you find it in the gut, it in, especially in the colon, it is associated with colorectal cancers and it's actually inside the colorectal cancer.

00:25:05.160 --> 00:25:13.680
And if that colorectal cancer happens to go somewhere else in the body like the liver, and you take that tumor outta the liver, it's inside the tumor that's in the liver.

00:25:13.740 --> 00:25:18.930
So I mean, this is like, I'm trying to get onco biome to like really catch on and I'm like, that's what it is.

00:25:18.930 --> 00:25:22.109
It's an onco biome oncology cancer biome.

00:25:22.109 --> 00:25:23.819
Like it's a specific to that cancer.

00:25:23.819 --> 00:25:24.599
But we'll see.

00:25:24.720 --> 00:25:25.740
We'll see if it evolves.

00:25:25.740 --> 00:25:28.619
There's a few papers that use the term, but it's not commonplace yet.

00:25:28.813 --> 00:25:31.153
I encourage all of our listeners to go talk about onco biomes.

00:25:31.202 --> 00:25:46.826
well, what I, what I thought was interesting is I found, um, something that talked about how the biodiversity of the gut in younger colorectal cancer patients is different than the diversity of the microbiome in older patients with colorectal cancer.

00:25:46.855 --> 00:25:48.506
I thought that was really interesting too.

00:25:48.980 --> 00:25:51.026
You mean it's less diverse or

00:25:51.145 --> 00:25:55.486
they had less diversity than with an older patient.

00:25:55.846 --> 00:25:56.056
Okay.

00:25:56.450 --> 00:26:08.536
so that's like another thing where it is not necessarily the same environment, and so what some of the things that might be altering a microbiome, the medications that we take, antibiotics,

00:26:08.790 --> 00:26:11.730
Antibiotics are independently linked to higher risks of cancer.

00:26:11.730 --> 00:26:14.221
Various cancers, breast cancers, colorectal cancers.

00:26:14.221 --> 00:26:18.780
There's many cancers that are associated with higher antibiotic use in the past.

00:26:18.780 --> 00:26:20.730
And so what, what would higher use be?

00:26:20.730 --> 00:26:22.770
Is there a definition for what's higher use?

00:26:22.875 --> 00:26:27.165
No, it's a, it's a dose, linked association though.

00:26:27.609 --> 00:26:35.980
The higher your antibiotic use in the past, it associates with a higher rate of incident cancer later.

00:26:36.154 --> 00:26:42.309
And so that would, that would have to do with your diversity of what's living in your, in your gut.

00:26:42.576 --> 00:26:43.385
Absolutely.

00:26:43.385 --> 00:26:47.016
Maybe we did use antibiotics more in certain decades than others.

00:26:47.046 --> 00:26:49.445
'cause we, we backed off, but only more recently

00:26:49.790 --> 00:26:50.766
No, that's true.

00:26:50.826 --> 00:26:51.395
Yeah.

00:26:51.556 --> 00:26:52.756
they're being used a little bit less.

00:26:52.756 --> 00:26:56.115
But man, I think they were, antibiotics were given out like candy in the, in the eighties.

00:26:56.115 --> 00:26:56.655
Nineties,

00:26:56.911 --> 00:27:07.688
Well in, in seventies, I mean, in our, you know, more our kind of growing up generation, um, whether or not you were a C-section baby that definitely plays a part in your microbiome.

00:27:08.288 --> 00:27:08.678
yes.

00:27:08.722 --> 00:27:11.678
'cause you get your organisms from the vaginal canal.

00:27:12.202 --> 00:27:12.653
Yeah.

00:27:12.950 --> 00:27:14.779
Um, breastfeeding.

00:27:15.769 --> 00:27:16.640
Were you breastfed?

00:27:16.640 --> 00:27:17.240
Were you bottle fed?

00:27:17.269 --> 00:27:20.119
And so all of these, you know, there are trends, right?

00:27:20.119 --> 00:27:32.160
I mean, when I was a baby, I think I was breastfed for a few months and, you know, that, that whole formula thing, like when I guess formula came out, it was a godsend, right?

00:27:32.190 --> 00:27:33.119
I mean, it just kind of.

00:27:33.349 --> 00:27:34.430
Save time.

00:27:34.490 --> 00:27:38.869
Women could work You know, like if their babies were fed formula, they could go back to work.

00:27:39.276 --> 00:27:41.405
and then it started to trend back to breastfeeding.

00:27:43.026 --> 00:27:51.395
So it, yeah, it is interesting to see like that, you know, even with, with having a c-section, you know, you have one child as a C-section and then all your children are C-section.

00:27:51.425 --> 00:27:53.190
I don't believe that's how it is anymore.

00:27:53.932 --> 00:27:56.722
your diet, I mean, that's kind of like the most obvious thing, right?

00:27:56.722 --> 00:27:57.863
Like your diet.

00:27:57.952 --> 00:28:00.712
How does that affect your microbiome?

00:28:00.742 --> 00:28:01.522
It's everything.

00:28:01.730 --> 00:28:02.630
it's everything.

00:28:02.720 --> 00:28:05.299
Generally speaking, diversity in the gut.

00:28:05.329 --> 00:28:08.539
If we're just talking about what's going on in the GI tract, diversity is your friend.

00:28:09.289 --> 00:28:13.789
so you do want diversity means that there's a lot of different types of organism.

00:28:14.089 --> 00:28:16.279
There's a lot of variety in there.

00:28:16.440 --> 00:28:21.829
So diversity is your friend, diversity in your gut, which comes from diversity in your diet of plant foods.

00:28:22.115 --> 00:28:22.565
Yeah.

00:28:22.880 --> 00:28:23.299
Yes.

00:28:23.914 --> 00:28:29.855
So that's, that's if, yeah, if, if you wanna know what to do, you eat more color, it always comes back down to the same thing, same advice.

00:28:30.335 --> 00:28:33.454
Eat a lot of plants and a lot of different types and a lot of different colors.

00:28:33.934 --> 00:28:41.555
Leaves and stems and flowers and roots and tubers and, you know, mix it all up and you'll eventually, um, have a very diverse and healthy gut.

00:28:41.740 --> 00:28:46.827
And we've talked about before, having that 30 different plants in your diet a week.

00:28:46.857 --> 00:28:52.637
So that includes the spices, the herbs, you know, your grains, all of that legumes.

00:28:52.637 --> 00:28:53.778
I like saying legumes.

00:28:54.048 --> 00:28:54.468
Yeah.

00:28:54.768 --> 00:29:00.738
You know, and probably the easiest way to do that is you have a little chart that you can, that's almost like a little laminated thing.

00:29:00.738 --> 00:29:02.657
They, they sell these, usually it's for kids.

00:29:02.657 --> 00:29:04.357
'cause we're we're trying to get kids to eat better.

00:29:04.688 --> 00:29:11.377
and just make sure that that day they had something yellow, something red, something in the blue spectrum could be blackberries that counts.

00:29:11.377 --> 00:29:12.248
Accounts purple.

00:29:12.817 --> 00:29:14.407
So just make sure that there's lots of color.

00:29:14.528 --> 00:29:20.647
And if you do that, you know, every day, all the colors, you'll probably get enough variety.

00:29:20.647 --> 00:29:21.458
Doritos don't count.

00:29:21.458 --> 00:29:22.298
I always have to add that.

00:29:22.538 --> 00:29:25.357
'cause that's the first thing people ask me is like, Doritos.

00:29:25.357 --> 00:29:25.448
And

00:29:25.478 --> 00:29:26.123
Oh, you're kidding.

00:29:26.153 --> 00:29:27.053
Oh, that's funny.

00:29:27.067 --> 00:29:27.337
Yeah.

00:29:27.530 --> 00:29:31.941
Well,'cause I think like Cheetos and Doritos leave all that orange stuff on your hand, so it's the first thing people think

00:29:31.986 --> 00:29:37.506
that's not, I mean, and they are plant-based, so I guess I could see their argument there.

00:29:37.746 --> 00:29:42.799
But, um, yeah, and, and again, even the brown foods, right, the grains, the beans.

00:29:43.174 --> 00:29:43.355
Mm-hmm.

00:29:43.910 --> 00:29:45.230
Don't dismiss those either.

00:29:45.230 --> 00:29:47.089
It doesn't just have to be what's in the rainbow.

00:29:47.089 --> 00:29:48.920
It could be just what's in the full spectrum.

00:29:49.160 --> 00:29:50.480
Look, the Crayola box.

00:29:50.480 --> 00:29:51.920
Let's start, let's start that.

00:29:51.950 --> 00:29:52.519
Eat the,

00:29:53.194 --> 00:29:53.914
Eat the Crayola.

00:29:54.394 --> 00:29:56.105
But is it the 16 count or

00:29:56.150 --> 00:29:56.839
No, it's the same.

00:29:56.839 --> 00:29:58.039
I'm going for the 64.

00:29:58.039 --> 00:30:00.109
The big box with, with the big box.

00:30:00.109 --> 00:30:00.230
With

00:30:00.575 --> 00:30:02.615
Well, I, I'm thinking daily.

00:30:02.615 --> 00:30:03.424
You're thinking weekly.

00:30:03.494 --> 00:30:05.180
I'm thinking we, yeah, I'm, I'm going.

00:30:05.180 --> 00:30:07.369
But that, in that case it would be the 32.

00:30:07.369 --> 00:30:09.680
Anyways, uh, we're, we're digressing.

00:30:15.088 --> 00:30:15.419
okay.

00:30:15.419 --> 00:30:24.219
And so then speaking of, of diet influencing the microbiome diet in itself, the highly processed

00:30:24.278 --> 00:30:24.969
Calorically.

00:30:24.969 --> 00:30:25.689
Dense.

00:30:26.259 --> 00:30:33.128
ultrapro, calorically, dense, nutritionally lacking devoid, that's a good word.

00:30:33.459 --> 00:30:36.159
Um, foods, uh, sedentary lifestyle.

00:30:36.781 --> 00:30:37.622
obesity.

00:30:37.652 --> 00:30:39.422
Obesity is a risk factor.

00:30:39.902 --> 00:30:43.291
Yeah, so, so each of those are independent risk factors.

00:30:43.291 --> 00:30:50.612
And when we say that, that means that there are plenty of studies to show that ultra processed food is associated with higher risk.

00:30:50.642 --> 00:30:54.979
And I do think we have introduced those multi-generational now, right?

00:30:55.249 --> 00:31:00.842
So we have people who grew up on highly processed food and then went on to have children on highly processed food.

00:31:01.021 --> 00:31:03.811
So I think some of those epigenetic effects are due to.

00:31:03.878 --> 00:31:09.278
Some of the multi-generational now changes in our diet, in our, in our lifestyle.

00:31:09.278 --> 00:31:15.082
So yes, the calorically dense foods that lead to obesity in our sedentary lifestyle,

00:31:15.771 --> 00:31:16.761
Sedentary lifestyle.

00:31:16.761 --> 00:31:23.211
I mean, we had PE in school, you know, are kids still going out and playing pe?

00:31:23.811 --> 00:31:24.471
I don't have kids.

00:31:24.471 --> 00:31:24.951
I don't know.

00:31:25.132 --> 00:31:28.281
But it seems like a lot of things are getting cut in our schools

00:31:28.632 --> 00:31:36.852
know, that's a really good point because if we say highly processed food is associated with cancer, exercise is associated with less cancer.

00:31:36.852 --> 00:31:40.422
So another way to frame all of this is exactly that.

00:31:40.422 --> 00:31:42.402
What if we stopped doing that was.

00:31:42.554 --> 00:31:54.656
Anti-cancer, like maybe what we should be looking at is not what causes it, but what was preventing it in the first place and making sure that we add those back, which is a little bit more empowering than just saying, you know, what causes it.

00:31:54.656 --> 00:31:57.027
And again, there may still be PE in schools.

00:31:57.507 --> 00:32:03.824
I just remember it was like an hour of, playing soccer or softball or volleyball or whatever.

00:32:04.108 --> 00:32:11.219
So let's be honest, there was that hour and then there was all sorts of other hours because we didn't come home and jump on a game box.

00:32:11.398 --> 00:32:13.888
We came home and went and did stuff.

00:32:14.086 --> 00:32:14.686
That's true.

00:32:14.686 --> 00:32:15.257
Yeah.

00:32:15.362 --> 00:32:16.981
We didn't, we didn't sit around.

00:32:17.011 --> 00:32:20.461
We literally didn't just sit down'cause we were kids and we had a lot of energy.

00:32:20.912 --> 00:32:29.402
And so, and I'm thinking just in, even in school, it would be like I had a free period and you know, we'd ask the gym teacher, can we borrow the cross country skis and try to, you know, go down the hill over there.

00:32:29.402 --> 00:32:30.301
And she's like, okay, sure.

00:32:30.662 --> 00:32:31.801
So we did all sorts of things.

00:32:32.071 --> 00:32:32.432
Okay.

00:32:32.461 --> 00:32:43.321
You went to a completely different school than We never had cross country skiing in any of the schools I was at, but, um, that's, that sounds kind of fun actually.

00:32:43.951 --> 00:32:49.321
but yeah, I was in drama and so we were dancing, you know, we were doing all of that sort of thing.

00:32:49.592 --> 00:32:54.471
But yeah, we weren't sitting around in front of a, a monitor playing games.

00:32:54.531 --> 00:32:57.622
I did watch a lot of tv, but yeah.

00:32:57.652 --> 00:33:03.172
But I would also go in the backyard and, you know, try to practice softball'cause I was horrible at it.

00:33:03.172 --> 00:33:05.409
Or climb trees, all of that stuff.

00:33:05.469 --> 00:33:06.608
We were outside more.

00:33:06.755 --> 00:33:09.707
It doesn't explain why our generation also is getting,

00:33:09.721 --> 00:33:18.954
Well, we were outside more, but we also were not being monitored, so maybe we were like literally like the classic, be home by dark.

00:33:19.171 --> 00:33:24.601
And so it's, I don't know about you, but I went all the way down to the park in the village, across the golf course, down the hill.

00:33:24.990 --> 00:33:25.621
I'm like,

00:33:25.800 --> 00:33:27.316
oh, we were riding our bikes.

00:33:27.316 --> 00:33:27.705
Like

00:33:27.835 --> 00:33:33.115
yeah, at very young ages we were out and about going, traveling around is my point.

00:33:33.115 --> 00:33:33.565
So that,

00:33:33.695 --> 00:33:34.895
we sound like old people.

00:33:34.895 --> 00:33:36.276
We sound like old people right now.

00:33:36.276 --> 00:33:40.655
Being like, back in my day I used to walk uphill both ways to school.

00:33:40.895 --> 00:33:41.165
yeah.

00:33:41.165 --> 00:33:47.766
But definitely it's, it does seem, it, I mean even my, like now I feel like I'm more sedentary with social media.

00:33:47.766 --> 00:33:49.955
Like I'm way more sedentary than I used to be.

00:33:50.240 --> 00:33:51.080
Oh yeah, me too.

00:33:51.306 --> 00:33:52.445
Like it's,

00:33:52.941 --> 00:33:56.488
this, these screens that were staring at a lot of my work is on a screen.

00:33:56.548 --> 00:33:56.907
Yeah.

00:33:57.205 --> 00:33:57.625
Yeah.

00:33:57.675 --> 00:33:59.865
Admittedly, I'm not out and about.

00:34:00.005 --> 00:34:00.755
Going to the park?

00:34:00.958 --> 00:34:17.307
no, but I am currently in Tucson and it is lovely weather here, and I have been walking the dog for about half an hour a day, which isn't a terrible long time to walk, but I wear a weighted vest even to kinda up my game.

00:34:17.987 --> 00:34:21.617
So there's 30 minutes of my 150 minutes.

00:34:21.976 --> 00:34:22.967
A week

00:34:23.416 --> 00:34:23.746
right?

00:34:24.137 --> 00:34:25.186
my exercise.

00:34:25.358 --> 00:34:26.708
And so I have been doing that.

00:34:26.708 --> 00:34:32.664
I've been here, I don't know how many days, but yeah, I mean it's a good habit to get into moving.

00:34:32.844 --> 00:34:33.385
moving.

00:34:33.835 --> 00:34:39.744
Even if, and this is something I would tell my patients all the time, just put on some music.

00:34:39.744 --> 00:34:41.623
Put on a song, and dance to it.

00:34:41.623 --> 00:34:42.554
Everyone's got a song.

00:34:42.876 --> 00:34:44.646
You don't like dancing, just move to it.

00:34:44.963 --> 00:34:45.472
Move.

00:34:45.893 --> 00:34:46.282
I like it.

00:34:46.492 --> 00:34:47.182
so, anyways, okay.

00:34:47.182 --> 00:34:55.103
So yeah, so, another thing that I have read is a theory as to why there may be you know, more diagnoses of cancer in young people.

00:34:55.293 --> 00:34:55.922
sleep.

00:34:56.913 --> 00:35:04.833
'cause we were talking about devices, um, being on social media, all of that causes alterations to our sleep cycle.

00:35:05.012 --> 00:35:07.382
And so sleep is when our body repairs.

00:35:07.382 --> 00:35:09.362
If you're not getting a.

00:35:09.362 --> 00:35:13.197
That repairing going on, that is bad.

00:35:13.257 --> 00:35:13.947
That's really bad.

00:35:14.577 --> 00:35:14.797
Yes.

00:35:15.277 --> 00:35:18.103
I think if people do wanna pursue that as.

00:35:18.748 --> 00:35:28.137
Where the evidence is light at night, LAN has been studied extensively and light at night is associated with higher cancer incidents.

00:35:28.467 --> 00:35:29.847
we have a lot of light at night now.

00:35:30.297 --> 00:35:33.898
I mean, all you have to do is look at a map and see how bright cities are.

00:35:34.197 --> 00:35:35.608
You can see it from satellite images.

00:35:35.847 --> 00:35:38.547
there's something called clock genes that's probably at the heart of this.

00:35:38.577 --> 00:35:46.137
So we should respect the circadian rhythm that we associate with our best health and our best function.

00:35:46.137 --> 00:35:51.027
That is you sleep at night and you're awake in the day, you eat in the daytime, you don't eat in the night.

00:35:51.057 --> 00:35:59.987
You know, there's these little cues, biological cues that you send your body, that help it normalize its function, whether it's immune function or endocrine function.

00:36:00.427 --> 00:36:02.947
and certainly brain function is best when you.

00:36:03.322 --> 00:36:08.782
Get a good deep sleep, you get these waves of glymphatic that clear the brain.

00:36:08.782 --> 00:36:11.722
And so there's no downside to this is my point.

00:36:11.722 --> 00:36:16.822
And if you don't, if you do have light at night when you're sleeping, put something on, put a mask on, um,

00:36:16.882 --> 00:36:17.663
Eye mask,

00:36:17.963 --> 00:36:18.353
yeah.

00:36:18.413 --> 00:36:18.833
Put a eye

00:36:19.012 --> 00:36:19.432
a sleep eye

00:36:19.463 --> 00:36:20.483
Mm-hmm.

00:36:20.682 --> 00:36:20.922
Yeah.

00:36:20.922 --> 00:36:24.132
If you can't make it pitch dark, then, then that's your second way of doing it.

00:36:24.132 --> 00:36:28.603
And a lot of folks like to do that because then you can pick the mask up if you have to go to the bathroom and see where you're going.

00:36:28.932 --> 00:36:42.293
The other thing you can do is, because there are devices, like we have a HEPA filter in our room and I put tape over the little light'cause there's like a dim function where you can kind of dim the light of the HEPA filter, but there's still a little light.

00:36:42.652 --> 00:36:46.643
And so you could just put like several layers of, you know, tape over that light.

00:36:47.182 --> 00:36:47.663
Yes.

00:36:47.813 --> 00:36:48.742
Very important.

00:36:48.742 --> 00:36:49.342
It's essential.

00:36:49.342 --> 00:36:55.012
This is like foundational, this is like eating your veggies, get, get a good night's sleep.

00:36:55.012 --> 00:36:57.333
And total darkness is really important.

00:36:57.992 --> 00:37:00.677
the last thing we wanted to talk about was early detection, right?

00:37:01.277 --> 00:37:06.788
I mentioned it a little bit early in the show, but detecting things earlier is always a good idea.

00:37:07.523 --> 00:37:14.452
Well it And is that, why is early detection, why, you know, because imaging is getting so much better.

00:37:14.452 --> 00:37:17.452
Is that why more cancers are being found?

00:37:17.648 --> 00:37:18.427
Mm,

00:37:18.900 --> 00:37:21.826
are, is it just because like imaging is so much better?

00:37:22.081 --> 00:37:25.320
I don't think so because most of the colorectal cancer is stage three and four.

00:37:26.130 --> 00:37:30.735
That would've been picked up on, um, CAT scan of 20 years ago still would've picked it up.

00:37:31.432 --> 00:37:32.873
Oh, I do wanna say this though.

00:37:33.293 --> 00:37:35.032
I don't think this is connected to Covid at all.

00:37:35.259 --> 00:37:42.099
Like I should say, we can't blame the Covid pandemic in any way because a lot of this has happening in prior to 2020.

00:37:42.324 --> 00:37:42.673
Right.

00:37:42.759 --> 00:37:47.648
So there were, uh, there were the conspiracy theories that it was not only Covid, but it was also the Covid vaccine.

00:37:48.036 --> 00:37:53.496
this trend of younger people being diagnosed with cancer started in the nineties.

00:37:54.036 --> 00:37:54.425
Yeah.

00:37:54.936 --> 00:37:55.235
Yeah.

00:37:55.235 --> 00:37:56.436
And it's just gone up since.

00:37:56.849 --> 00:38:10.927
I will say this though, whether it is infection or a vaccine, anything that causes systemic inflammation to be kicked up can cause cancer to grow faster at that time, progress faster.

00:38:11.467 --> 00:38:20.347
So systemic inflammation, whenever there's a tumor, systemic inflammation generally means that it's going to grow, it's gonna cause it to grow.

00:38:20.347 --> 00:38:29.648
We've done this in animals repeatedly'cause we have an experimental model with animals where the poor little things we, we create inflammation in their little paw pads and then we see what happens in other parts of their body.

00:38:30.398 --> 00:38:30.788
So.

00:38:31.268 --> 00:38:36.277
We've done this multiple times with, in multiple experiments with animals, and I don't think it's any different for humans.

00:38:36.277 --> 00:38:40.088
Systemic inflammation can cause a cancer to grow.

00:38:40.538 --> 00:38:44.507
It could be caused by, Infections that aren't being addressed.

00:38:44.987 --> 00:38:54.181
Um, different exposures there was an article from University of Chicago and they were talking about chronic inflammation as being a potential reason.

00:38:54.496 --> 00:38:55.186
Yeah.

00:38:55.425 --> 00:39:02.085
Chronic inflammation is a potential reason, and you still need the microbiome in that area to be.

00:39:02.264 --> 00:39:02.833
Skew.

00:39:03.228 --> 00:39:05.507
there was a model, it was actually done in the journal science.

00:39:05.507 --> 00:39:16.264
It was a model where they used h pylori and they, they proved that h pylori was connected to stomach cancer, but only under certain conditions, and it had to be chronic inflammatory conditions.

00:39:16.264 --> 00:39:22.503
And that is one of the cancers that, um, we are seeing more and more young people getting gastric cancer.

00:39:22.554 --> 00:39:29.193
Yeah, and I, I'm sure that's a delay of diagnosis because generally speaking, that's not gonna be suspect in people who are young.

00:39:29.403 --> 00:39:34.114
it's not as common as breast and prostate and colorectal cancers and other cancers like that.

00:39:34.114 --> 00:39:37.443
So it's gonna be way, way down on a doctor's differential diagnosis.

00:39:37.864 --> 00:39:41.110
So yeah, I could see how that's a delay of diagnosis a lot of the time too.

00:39:41.293 --> 00:39:56.934
another possible theory was, people were giving birth later, they were having fewer children, and also, waiting to have children and that would lead to a higher risk of breast cancer and potentially ovarian and uterine cancer.

00:39:57.081 --> 00:39:57.681
Interesting.

00:39:57.753 --> 00:39:58.114
Sure.

00:39:58.173 --> 00:39:58.384
Yeah.

00:39:58.641 --> 00:40:00.275
having children lowers your risk.

00:40:00.536 --> 00:40:01.311
And I think.

00:40:01.751 --> 00:40:14.610
A really big one, um, that we see in the United States healthcare disparities, so people not having access to, medicine, to doctors, to healthy food.

00:40:15.391 --> 00:40:22.273
That in itself is a risk factor for cancer at any age, but, um, definitely can affect younger people.

00:40:23.009 --> 00:40:27.568
I I think that most people probably don't get taken very seriously when they go in.

00:40:27.748 --> 00:40:34.998
If you're under 45 and you have symptoms, they're gonna think it's other things so, so the other piece of advice is be persistent.

00:40:35.539 --> 00:40:40.188
If you do see the doctor and they don't help you go back and tell them That didn't work.

00:40:40.248 --> 00:40:40.878
What else you got?

00:40:41.358 --> 00:40:46.918
So I think it's really important to not, stop until you're symptom free is really basically it.

00:40:46.918 --> 00:40:51.478
And that should be not stop until you have a good diagnosis.

00:40:51.528 --> 00:40:52.429
'cause even without symptoms.

00:40:52.429 --> 00:40:55.219
You can, you can allay a symptom but still have the problem underlying it.

00:40:55.503 --> 00:40:58.239
You know, you could take a drug and stop, uh, I don't know.

00:40:58.239 --> 00:40:59.619
You could stop diarrhea.

00:40:59.833 --> 00:41:03.463
And, and well that's not really helping if you don't have a proper diagnosis.

00:41:03.463 --> 00:41:06.074
So always make sure you know the condition that's causing it.

00:41:06.074 --> 00:41:13.384
And if you're not getting that persist, it's not always easy to advocate, self-advocate, but, you know, bring someone who likes to do that kind of stuff.

00:41:13.384 --> 00:41:15.273
There's, we all have those people in our lives.

00:41:15.664 --> 00:41:17.253
I am one of those people, so I know.

00:41:20.278 --> 00:41:20.489
Okay.

00:41:20.489 --> 00:41:23.998
So we've been talking mostly about like breast and colorectal.

00:41:23.998 --> 00:41:25.289
We mentioned gastric cancer.

00:41:25.768 --> 00:41:31.139
So what are the cancers that we are seeing higher incidence in younger patients?

00:41:31.518 --> 00:41:31.938
Mm-hmm.

00:41:32.039 --> 00:41:33.943
At, at least in the us.

00:41:34.094 --> 00:41:44.893
Um, according to the American Cancer Society, the most common cancers in young adults are breast cancer lymphomas, both non-Hodgkin and Hodgkin melanoma sarcomas.

00:41:45.534 --> 00:41:47.514
cancers of the female genital tract.

00:41:47.574 --> 00:41:55.974
So that's cervical and ovarian cancers, thyroid cancer, testicular cancer, colorectal cancer brain and spinal cord tumors.

00:41:56.063 --> 00:42:00.204
So those are the most common, according to the American Cancer Society here.

00:42:00.764 --> 00:42:02.673
doesn't mean they're all increasing in incidences.

00:42:02.844 --> 00:42:06.463
We have talked about a couple that are, but those are the ones to look out for

00:42:06.804 --> 00:42:15.018
Yeah, and I had read that, those cancers, so colorectal, breast, prostate, uterine, gastric, small intestine.

00:42:15.469 --> 00:42:23.838
Kidney and pancreatic cancers are three times higher in patients born in 1990 versus 1955.

00:42:23.838 --> 00:42:24.469
oh, wow.

00:42:24.588 --> 00:42:25.458
Three times higher.

00:42:25.458 --> 00:42:26.389
That's, that's a lot.

00:42:26.438 --> 00:42:26.829
Yeah.

00:42:27.548 --> 00:42:33.759
Well, and I just wanna say the other thing, which is, you know, maybe people are curious, like, how do I know my symptoms, even a symptom of cancer?

00:42:33.759 --> 00:42:37.239
And I'm gonna go through the quick list by the American Cancer Society for that too.

00:42:37.693 --> 00:42:41.324
an unusual lump or swelling, especially in the neck, breast, belly or testicle.

00:42:41.983 --> 00:42:44.204
So get that checked out if you feel something.

00:42:44.384 --> 00:42:44.954
Unexplained.

00:42:44.954 --> 00:42:46.693
Tiredness and loss of energy.

00:42:46.873 --> 00:42:48.903
And that's usually profound, right?

00:42:49.353 --> 00:42:54.273
Easy bruising, abnormal bleeding, pain in one part of the body that just won't go away.

00:42:54.664 --> 00:42:56.974
Unexplained fever that won't go away.

00:42:57.153 --> 00:43:06.063
Frequent headaches sometimes if that headache comes along with vomiting, obviously not if you have a cold or a flu, but if it happens repeatedly, I would put on here night sweats.

00:43:06.213 --> 00:43:08.403
So middle of the night you get all hot and sweaty.

00:43:08.764 --> 00:43:09.664
that's my own addition.

00:43:10.204 --> 00:43:14.804
Sudden eye or visual changes, loss of appetite or unplanned weight loss.

00:43:15.119 --> 00:43:16.708
Don't explain it away.

00:43:17.039 --> 00:43:19.539
If you have unplanned weight loss, you do need to get that checked out.

00:43:19.719 --> 00:43:24.608
And then of course, for your skin, a new mole or other spot on the skin or one that changes.

00:43:24.608 --> 00:43:25.909
Shape, color, or size.

00:43:26.478 --> 00:43:28.458
That's all the signs or symptoms.

00:43:28.588 --> 00:43:34.708
And then some considerations for younger adults when they are diagnosed with cancer.

00:43:34.809 --> 00:43:39.105
talking to your doctor about, fertility preservation is really important.

00:43:39.625 --> 00:43:55.590
treatments can cause sterility so whether, so whether that's, you know, like a sperm bank or cryo-preservation, where you're retrieving eggs and saving those, you know, those are really important conversations to have.

00:43:55.990 --> 00:43:57.760
and I think that's frequently missed.

00:43:58.190 --> 00:44:02.206
and then how do you talk to your kids after you've been diagnosed?

00:44:02.206 --> 00:44:08.326
Finding someone, finding resources to help you talk with your children after a cancer diagnosis.

00:44:08.726 --> 00:44:17.815
you can talk with your care team and see if they have resources for you, and then talking to people about, you know, the, the impact on, on your work.

00:44:17.876 --> 00:44:19.735
You know, do you talk to your employers?

00:44:19.786 --> 00:44:24.436
how do you like juggle going through treatment and working,

00:44:24.465 --> 00:44:25.155
Most can.

00:44:25.155 --> 00:44:30.541
Centers do have, counselors and social workers, and I think they're underutilized.

00:44:30.951 --> 00:44:32.570
I think you shouldn't wait for a referral.

00:44:32.751 --> 00:44:34.371
You need to advocate for that too.

00:44:34.780 --> 00:44:36.161
I think it's really helpful.

00:44:36.161 --> 00:44:42.101
I think it's something that we as professionals should also make more use of.

00:44:42.731 --> 00:44:49.780
I mean, it came to the point where I felt like everyone should do an interview with, with the team, whoever the counselors and social workers are at a given center.

00:44:50.291 --> 00:44:59.773
I know they don't, they're not usually staffed to the point where everyone can go see them, but boy, would that be awesome because then people don't have a, I don't know, what's the word I'm looking for?

00:45:00.614 --> 00:45:03.313
preconceived notion as to why they're being referred there.

00:45:03.313 --> 00:45:03.523
Right?

00:45:03.523 --> 00:45:09.074
Like, you know, I think PE it's hard for us to admit we need help sometimes and especially emotionally.

00:45:09.074 --> 00:45:12.554
So I think it'd be great if it was everybody got screened.

00:45:12.818 --> 00:45:20.833
I mean, both cancer centers I've worked at, they had patients during intake process, meeting with counselors and.

00:45:21.222 --> 00:45:24.012
Yes, making it universal removes the taboo.

00:45:24.402 --> 00:45:25.722
Yeah, for sure.

00:45:25.842 --> 00:45:42.112
I know one of the big concerns that I have seen on social media, and read in articles, the concerns about how do you date with cancer, with a cancer diagnosis, and talking about sex with an after cancer.

00:45:42.842 --> 00:45:51.943
these are big topics that, find someone to talk about that with, like, reach out, ask your oncologist, ask your team.

00:45:52.226 --> 00:45:58.244
Because there's physical and psychological barriers or hurdles often after cancer treatment.

00:45:58.478 --> 00:45:59.349
Absolutely.

00:45:59.789 --> 00:46:00.148
Okay.

00:46:00.148 --> 00:46:04.079
So, um, if you are listening and you are a.

00:46:04.079 --> 00:46:10.878
A person who has not been diagnosed with cancer and does not have a history of cancer, what are things you can do to reduce your risk?

00:46:11.119 --> 00:46:13.639
We've mentioned some of them so far.

00:46:13.938 --> 00:46:17.088
Trying to improve your sleep, your sleep, environment.

00:46:17.518 --> 00:46:21.418
adding diversity of plants to your diet.

00:46:21.418 --> 00:46:25.719
reducing ultra processed food, reducing processed meats, and reducing alcohol.

00:46:25.778 --> 00:46:27.969
These are things that we have talked about.

00:46:28.059 --> 00:46:29.289
Oh, increasing fiber.

00:46:29.318 --> 00:46:29.978
That's another one.

00:46:30.713 --> 00:46:32.088
So that's part of your plant foods.

00:46:32.088 --> 00:46:32.358
Right?

00:46:32.358 --> 00:46:33.349
You're increasing fiber.

00:46:33.349 --> 00:46:37.019
You're increasing those, those colors I think we've covered all of these.

00:46:37.394 --> 00:46:38.744
I know I was thinking the same thing.

00:46:38.744 --> 00:46:40.791
We've actually discussed each of these at length.

00:46:40.965 --> 00:46:41.206
Yeah.

00:46:41.206 --> 00:46:44.115
As I'm going through the list, I'm like, wait, that was this episode?

00:46:44.115 --> 00:46:44.865
That was that episode.

00:46:44.865 --> 00:46:45.166
I think.

00:46:45.510 --> 00:46:46.951
Did we talk about processed beets?

00:46:46.951 --> 00:46:49.021
I don't know, but I'm sure we've mentioned them before.

00:46:49.530 --> 00:46:49.740
yeah.

00:46:49.746 --> 00:46:52.411
And I mentioned how sleep is so foundational.

00:46:52.411 --> 00:46:55.291
We actually had two episodes on people who have trouble sleeping.

00:46:55.291 --> 00:47:06.831
So if people go back to that, we're very specific on what you can do, conventionally and with, with natural agents to help with sleep and,'cause there's different reasons that we, you know, wake up in the night or can't get to sleep in the first place or whatever.

00:47:06.831 --> 00:47:07.641
So we have addressed that.

00:47:07.641 --> 00:47:08.001
You're right.

00:47:08.001 --> 00:47:09.112
And then we've addressed alcohol.

00:47:09.161 --> 00:47:09.552
Yeah.

00:47:09.592 --> 00:47:10.581
we've addressed fiber.

00:47:10.581 --> 00:47:12.981
We just talked about ultra processed foods.

00:47:13.612 --> 00:47:15.802
So Yeah, actual items.

00:47:15.802 --> 00:47:17.902
We got all, we got all the resources for you.

00:47:18.211 --> 00:47:22.282
The ultra processed foods is in the, seed oil episode.

00:47:22.282 --> 00:47:23.782
So that's just our last episode before this one.

00:47:24.141 --> 00:47:24.592
Yeah.

00:47:24.621 --> 00:47:28.431
And we're both kind of excited about our next episode.

00:47:28.431 --> 00:47:29.032
Oh my gosh.

00:47:29.331 --> 00:47:37.371
Well, I really enjoy it because part of our assignment for research is watching Netflix and Hulu, which is one of my favorite things to do,

00:47:37.592 --> 00:47:44.822
So I wanna ask our listeners to do this too, where ask people to go ahead and watch some of these programs so that the follow up podcast will make sense,

00:47:45.197 --> 00:47:45.527
yeah.

00:47:45.527 --> 00:47:51.947
So we are talking about, fakes and frauds people who lied about having cancer.

00:47:52.217 --> 00:47:54.166
so we are watching Anatomy of Lies.

00:47:54.447 --> 00:48:00.987
which is, I gotta say this, which is about a writer who wrote for Grey's Anatomy and she was a faker of cancer.

00:48:01.302 --> 00:48:04.032
oh, she was a faker of so many things that, that is.

00:48:04.177 --> 00:48:05.527
So,

00:48:05.554 --> 00:48:06.784
Diabolical

00:48:06.784 --> 00:48:07.833
oh, it's just insane.

00:48:07.864 --> 00:48:08.494
It's insane.

00:48:08.704 --> 00:48:11.987
Um, and then why don't I remember the other things we watched?

00:48:12.487 --> 00:48:13.297
Scamanda.

00:48:13.427 --> 00:48:15.317
Oh, Scamanda, that's on Hulu.

00:48:15.606 --> 00:48:15.847
Yeah.

00:48:15.847 --> 00:48:19.626
That one feels a little bit like a Hallmark movie, but you know, it's still worth watching.

00:48:19.726 --> 00:48:29.567
the thing with Scamanda is it's a b, C news and so it's very much like if you were watching like Nightline or or one of those a b bbc Well, they, they like kind of, they, they repeat a lot of stuff.

00:48:29.987 --> 00:48:33.766
It's the one you can kind of be watching while you're doing something else'cause they repeat themselves.

00:48:34.456 --> 00:48:36.887
Yeah, I was doing a lot of rewinding it.

00:48:36.887 --> 00:48:37.996
It's really interesting.

00:48:38.027 --> 00:48:43.226
Um, and then the third one is we're gonna, to, we're gonna talk about Bell Gibson.

00:48:43.286 --> 00:48:44.126
And so,

00:48:44.177 --> 00:48:46.246
Not Mel Gibson, bell Gibson.

00:48:46.876 --> 00:48:54.556
Mel Gibson's a completely different episode, but yes, we are talking about Belle Gibson and I'm sure many of you have heard of her.

00:48:54.836 --> 00:48:59.157
she was in Australia and she.

00:48:59.184 --> 00:49:02.784
Pretended to have cancer and really created a huge following.

00:49:03.143 --> 00:49:05.583
Well, we'll go, we'll go into it more in, our next episode.

00:49:05.583 --> 00:49:06.693
So that's what we're recording next.

00:49:06.693 --> 00:49:09.724
And so right now we're just doing the research by watching these.

00:49:10.067 --> 00:49:10.996
We're doing the research.

00:49:11.117 --> 00:49:12.527
This is hard work folks.

00:49:12.677 --> 00:49:14.597
It's my favorite kind of research.

00:49:14.867 --> 00:49:18.467
Okay, so, um, again, thanks for listening.

00:49:18.467 --> 00:49:19.157
And

00:49:20.507 --> 00:49:22.121
That's a, that's a loose use of the term, but go ahead.

00:49:23.416 --> 00:49:28.927
again, if you like this episode, leave us a comment, leave us a review, a rating,

00:49:29.137 --> 00:49:30.246
Yeah, give us a shout out.

00:49:30.516 --> 00:49:32.266
Email us, you know, we're around.

00:49:32.340 --> 00:49:35.099
share the episode with your, with your friends and family.

00:49:35.309 --> 00:49:36.809
And consider us a resource when you need us.

00:49:37.427 --> 00:49:38.447
On that note, I'm Dr.

00:49:38.447 --> 00:49:39.137
Leah Sherman,

00:49:39.137 --> 00:49:39.706
And I'm Dr.

00:49:39.706 --> 00:49:40.327
Tina Kaczor.

00:49:40.364 --> 00:49:41.594
and this is the Cancer Pod.

00:49:41.594 --> 00:49:42.313
Until next time.