Welcome to The Cancer Pod!
Alcohol and Cancer, An Update 2025
Alcohol and Cancer, An Update 2025
What does it take to change the warning label on alcohol, an Act of Congress? (Oddly, yes! It DOES need an Act of Congress to happen.) More…
Choose your favorite podcast player
Jan. 22, 2025

Alcohol and Cancer, An Update 2025

Alcohol and Cancer, An Update 2025

 What does it take to change the warning label on alcohol, an Act of Congress? (Oddly, yes! It DOES need an Act of Congress to happen.) More importantly, how much alcohol does it take to raise your risk of getting cancer? Join Tina and Leah as they give context to the topic of alcohol and cancer and explain why the Surgeon General wants to change the warning label. They admit that they do not abstain from alcohol 100%... abstinence is a choice, though, so if you don't drink at all, good for you!

Prior episode: Good for You? or Bad for You? Alcohol
Ireland's strong alcohol label stance
How acetaldehyde from alcohol ingestion forms in your body
Which cancers are linked to alcohol consumption?

Support the show

Our website: https://www.thecancerpod.com
Join us for live events, and more!

Email us: thecancerpod@gmail.com

We are @TheCancerPod on:

THANK YOU for listening!

Chapters

00:01 - Excerpt from episode

01:22 - Intro

05:35 - Current guidelines for alcohol intake

07:00 - Is alcohol really linked to getting cancer?

10:08 - What is "a serving of alcohol" anyways?

11:09 - Which cancers are linked to alcohol consumption?

14:30 - How, exactly, does alcohol increase cancers?

19:25 - What about regular drinking in European countries?

24:11 - What can you do in lieu of alcohol?

27:52 - Wrap up

Transcript
WEBVTT

00:00:00.050 --> 00:00:04.347
this is a good recap of episode four for those who did not listen to us at that time.

00:00:04.722 --> 00:00:05.543
It's still online.

00:00:05.592 --> 00:00:08.022
It's still in your podcast player.

00:00:08.320 --> 00:00:09.442
I was really afraid.

00:00:09.452 --> 00:00:14.939
That episode really, I remember starting off and being really afraid that it was just going to like piss people off.

00:00:14.980 --> 00:00:15.789
But, you know, now

00:00:15.814 --> 00:00:15.894
I know.

00:00:16.019 --> 00:00:17.010
the Surgeon General behind

00:00:17.184 --> 00:00:17.565
Yeah.

00:00:17.821 --> 00:00:18.192
Yeah.

00:00:18.445 --> 00:00:19.565
Don't blame the messenger.

00:00:20.105 --> 00:00:20.964
We didn't make the data.

00:00:21.382 --> 00:00:23.411
We both have cocktails on occasion, too.

00:00:23.602 --> 00:00:25.891
So, like you said, there's nothing wrong with that.

00:00:25.902 --> 00:00:25.981
It's

00:00:26.207 --> 00:00:28.155
We all have one.

00:00:28.155 --> 00:00:28.641
Together.

00:00:28.641 --> 00:00:29.871
together on occasion.

00:00:30.812 --> 00:00:31.512
It's okay.

00:00:31.972 --> 00:00:34.661
We're, we're mindful of the risk we're taking at that moment.

00:01:22.326 --> 00:01:23.466
Happy New Year, Tina

00:01:23.870 --> 00:01:24.900
Happy New Year, Leah.

00:01:24.900 --> 00:01:35.450
So we're kind of starting the, the new year with, um, some news that isn't really news because it's something we covered like in episode four.

00:01:35.450 --> 00:01:37.070
Oh, yes.

00:01:37.301 --> 00:01:38.691
I said news that isn't really news.

00:01:38.700 --> 00:01:39.820
You know what I thought you were going to say?

00:01:40.710 --> 00:01:43.796
That 2025 we're going to do more news headlines.

00:01:43.990 --> 00:01:46.120
We are, that's actually probably a better way to start.

00:01:46.180 --> 00:01:46.751
Thank you Tina.

00:01:46.990 --> 00:01:54.911
Uh, we're gonna talk more about cancer in the news and, and yeah, the, this big news that's in all the headlines.

00:01:55.509 --> 00:01:58.938
It's kind of been known for at least 40 years

00:01:58.963 --> 00:01:59.634
Yes.

00:01:59.838 --> 00:02:01.769
and we talked about it four years ago.

00:02:01.989 --> 00:02:02.359
Yep.

00:02:02.381 --> 00:02:04.361
The evil demon alcohol.

00:02:04.396 --> 00:02:05.635
Yeah, yeah.

00:02:05.956 --> 00:02:11.126
So what started this whole conversation is the Surgeon General Vivek Murthy.

00:02:11.216 --> 00:02:18.044
He wants to put a warning label on alcohol saying that it can cause cancer.

00:02:18.653 --> 00:02:26.080
currently alcohol has the warning against, you know, drinking alcohol while pregnant and operating heavy machinery and driving that sort of thing.

00:02:26.500 --> 00:02:35.120
Yeah, I think that, I think there's a little, at the very end on the warning it says, and other health conditions, or something like that, something kind of vague about alcohol not being great for you.

00:02:35.574 --> 00:02:35.985
Yeah.

00:02:36.199 --> 00:02:38.008
And he wants it to really be strong,

00:02:38.313 --> 00:02:39.003
he does.

00:02:39.014 --> 00:02:39.524
He does.

00:02:39.544 --> 00:02:44.028
And if you like, look at the numbers, there's in the U.

00:02:44.028 --> 00:02:44.218
S.

00:02:44.229 --> 00:02:51.748
like a hundred thousand cases of cancer can be attributed to alcohol and 20, 000 cancer deaths

00:02:52.395 --> 00:02:53.395
attributed to alcohol.

00:02:53.450 --> 00:02:54.621
attributed to alcohol.

00:02:55.350 --> 00:02:55.700
Yeah.

00:02:55.721 --> 00:02:59.580
In terms of The cancers that are associated with alcohol consumption.

00:02:59.700 --> 00:03:00.151
Yeah.

00:03:00.431 --> 00:03:00.781
Yeah.

00:03:00.811 --> 00:03:12.585
My understanding when I was looking at some of these news briefs coming across is that in Ireland, they've already passed legislation that will put a very strong warning in 2026.

00:03:13.775 --> 00:03:27.919
alcohol causes aggressive cancers or something really like akin to the tobacco label that I see in Canada that said tobacco kills, you know, when we were kind of hedging over here, tobacco may cause cancer of the lung,

00:03:28.180 --> 00:03:28.620
Right.

00:03:29.865 --> 00:03:35.155
so I also read, confirmed this for me, cause I think you looked into this further than I did, but.

00:03:36.004 --> 00:03:41.655
It takes an act of Congress to change the label on the alcohol bottles, is that true?

00:03:41.870 --> 00:03:42.469
Yeah.

00:03:42.539 --> 00:03:43.569
Yeah, it does.

00:03:44.365 --> 00:03:49.865
That's actually, I mean, I shouldn't laugh, I just think that it's funny, don't we use that as like, what does it take, an act of Congress?

00:03:49.955 --> 00:03:50.275
You know.

00:03:50.745 --> 00:03:51.205
Yes,

00:03:51.312 --> 00:03:54.692
And I even watched an interview with the Surgeon General and he mentioned that.

00:03:54.692 --> 00:03:57.875
because he's, you know, we're about to change administrations.

00:03:57.875 --> 00:04:04.775
And so he was saying, but you know, it will take an act of Congress, but I guess back in the sixties, that's what they did with, um, tobacco warnings.

00:04:04.784 --> 00:04:05.134
So.

00:04:05.610 --> 00:04:06.009
Right.

00:04:06.039 --> 00:04:16.740
Well, for obvious reasons, because tobacco was a huge lobby group and they had the Congress people in their pockets, so of course they wanted it to be an act of Congress, that's why it took so darn long, even though we had evidence.

00:04:17.245 --> 00:04:27.134
Well, you know, what's really interesting is there's been all of this stuff about like, you know, wellness influencers and all of these people have been talking about things that are so bad for our health.

00:04:27.154 --> 00:04:32.060
And this whole alcohol thing, they haven't really said anything about.

00:04:32.661 --> 00:04:33.750
No one's touching it.

00:04:33.940 --> 00:04:35.540
No, it's so funny.

00:04:35.721 --> 00:04:38.240
And like people will get really like up in arms.

00:04:38.451 --> 00:04:41.341
And they're like, but, but, and I'm like, well, maybe you should check yourself.

00:04:41.370 --> 00:04:44.420
Maybe you should like see what your relationship with alcohol is.

00:04:44.451 --> 00:04:46.021
Why are you so upset?

00:04:46.560 --> 00:04:48.380
about this announcement.

00:04:48.721 --> 00:04:53.050
So, um, yeah, so that's what we're going to talk about today is alcohol and cancer.

00:04:53.490 --> 00:05:02.505
And we'll talk about, what the current alcohol guidelines are, which we've talked about all this, but then we're just going to rehash this and kind of bring it, to the forefront.

00:05:02.696 --> 00:05:10.975
yeah, the larger context to play devil's advocate is there's the cancer aspect, but people are more complex than just cancer.

00:05:11.305 --> 00:05:31.572
So, what are the recommendations in the You know, heart association world or the dementia groups, or, you know, like alcohol itself may not have a lot of redeeming qualities for health, but some of the vehicles do have other components that have been advocated for health, like wine and the resveratrol and polyphenols.

00:05:31.637 --> 00:05:31.927
Right.

00:05:31.927 --> 00:05:34.266
But it's the resveratrol, it's not the wine.

00:05:34.584 --> 00:05:34.915
Yeah.

00:05:34.915 --> 00:05:35.615
So, okay.

00:05:35.615 --> 00:05:37.694
the current guideline is.

00:05:37.898 --> 00:05:50.293
Like one drink a day for women and two drinks for men is what's the guideline, but in terms of safety, there actually is not any safe amount.

00:05:50.942 --> 00:05:50.952
Mm

00:05:51.362 --> 00:05:55.769
Let's say someone drinks like four glasses of wine a week.

00:05:55.829 --> 00:06:01.279
what is recommended is that you don't drink those all in one sitting, that it is spread out if you were to do that.

00:06:01.456 --> 00:06:03.057
But, just knowing that.

00:06:03.896 --> 00:06:05.916
There really isn't any safe level of alcohol

00:06:06.100 --> 00:06:13.423
Well, and I think when the people who created that guideline for the public were pressed as to how they found.

00:06:14.103 --> 00:06:17.483
A definitive one drink a day for women and two for men.

00:06:18.180 --> 00:06:24.170
They admitted that the only reason they did that was because they didn't think people would do zero.

00:06:24.970 --> 00:06:27.389
They didn't think people would abstain from alcohol.

00:06:27.519 --> 00:06:28.579
So they kind of

00:06:29.420 --> 00:06:29.879
hedged.

00:06:30.350 --> 00:06:30.939
They did.

00:06:31.009 --> 00:06:39.709
they put it there so that there was something, and It's more of a perception that people couldn't do abstinence from alcohol or that that might backfire maybe.

00:06:39.709 --> 00:06:40.180
I don't know.

00:06:40.180 --> 00:06:43.379
But in their interpretation, they said the data doesn't back it up.

00:06:43.379 --> 00:06:48.255
We just thought that this was more a practical way of doing it back in the day when they created the one for women, two for men.

00:06:48.552 --> 00:06:54.463
So I just thought, I thought that was kind of interesting, a little bit of artistic license with the science there.

00:06:54.713 --> 00:06:55.213
Yeah.

00:06:55.584 --> 00:06:55.884
Yeah.

00:06:55.894 --> 00:06:59.413
Because, because we just wouldn't be capable of avoiding it altogether.

00:06:59.937 --> 00:07:07.437
so one of the big things that came out, I think from the surgeon general's, statement is that.

00:07:07.584 --> 00:07:16.093
Alcohol is the third leading preventable cause of cancer behind smoking and obesity.

00:07:16.209 --> 00:07:16.829
Yeah.

00:07:17.031 --> 00:07:25.713
So everyone talks about preventing or reducing your risk of cancer, and, you know, you don't really hear that much about it.

00:07:25.834 --> 00:07:31.170
Again, I'm thinking of these wellness influencers and stuff, like nobody's talking about like avoiding your rosé

00:07:31.170 --> 00:07:41.100
No, you know, it's, it's harsh to do that because, you know, it's that inconvenient truth kind of idea where people get hit with that and they don't want to hear that.

00:07:41.201 --> 00:07:48.161
And so if you're an influencer, you want people following you, and if you give them bad news like that, that's not, that's not conducive to your brand.

00:07:49.103 --> 00:07:51.413
I know, but I, you know, like I've found it for so long.

00:07:51.413 --> 00:08:13.874
I've found it so cringy whenever it's like October and like, you know, breast cancer awareness month and there are like wine gatherings or special bottles of wine with pink ribbons on them, all that pink washing, and it's around alcohol or anything where it's like some sort of fundraiser, I'm not saying like a general fundraiser, maybe like with a big dinner and everything.

00:08:13.874 --> 00:08:16.759
But if it's like, I can't think of anything in specific.

00:08:16.858 --> 00:08:18.309
I think of things specifically.

00:08:18.309 --> 00:08:26.809
I don't want to say their names, but anything where it's like, Something in beer, you know, maybe like yoga and wine for breast cancer.

00:08:26.809 --> 00:08:28.478
I don't know if that exists, but it probably does.

00:08:28.649 --> 00:08:30.389
You know, I just think that's so cringy

00:08:30.791 --> 00:08:31.781
Yeah, I understand.

00:08:31.922 --> 00:08:32.292
Yeah.

00:08:33.032 --> 00:08:33.892
Cause you're a purist.

00:08:33.902 --> 00:08:35.812
And now here's my pure.

00:08:36.461 --> 00:08:36.772
Yeah.

00:08:37.022 --> 00:08:40.241
Because you're literally saying that that's a carcinogen you're giving out

00:08:40.831 --> 00:08:41.341
right?

00:08:41.351 --> 00:08:47.322
It's like, it's like, let's do a lung cancer, fundraiser with, uh, radon and cigarettes, you know?

00:08:47.692 --> 00:08:48.361
Yeah.

00:08:48.542 --> 00:08:49.032
Yeah.

00:08:49.469 --> 00:08:50.639
So here's the big picture.

00:08:50.649 --> 00:08:51.708
Here's my question.

00:08:51.818 --> 00:08:53.839
It's clearly carcinogenic.

00:08:54.198 --> 00:08:55.458
I mean, that's not even disputed.

00:08:55.458 --> 00:08:56.288
I mean, the science is there.

00:08:56.288 --> 00:09:04.178
We can talk about that There is some data showing that people who a drink had less neurodegeneration.

00:09:05.774 --> 00:09:08.254
For example, so, so my

00:09:08.485 --> 00:09:09.644
A drink of what?

00:09:09.705 --> 00:09:10.424
A drink of what?

00:09:10.674 --> 00:09:11.325
alcohol,

00:09:11.634 --> 00:09:12.595
Any alcohol.

00:09:12.764 --> 00:09:15.605
I think it was various types of alcohol, like a drink a day.

00:09:16.554 --> 00:09:29.504
So I'm only saying this because in the real world, let's face it, someone has a half a glass of wine or a smidge of something and it takes their stress from, a super high level to a lower level.

00:09:29.815 --> 00:09:30.434
I don't know.

00:09:30.495 --> 00:09:31.934
Some, sometimes I'm like, I don't know.

00:09:31.934 --> 00:09:32.924
Like, yeah, you're, you're right.

00:09:33.715 --> 00:09:44.914
Doing a detriment in the long run because it's clearly carcinogenic, but at that moment does the De stressing give you enough benefit for your overall health that it cancels out.

00:09:44.924 --> 00:09:45.205
You know what I

00:09:45.345 --> 00:09:45.735
Yeah.

00:09:45.735 --> 00:09:49.274
I mean, then that would be trying to find a different way to de stress

00:09:49.278 --> 00:09:49.437
for

00:09:49.465 --> 00:09:51.674
To To replace it.

00:09:52.235 --> 00:09:52.644
yeah,

00:09:53.024 --> 00:10:04.184
yeah, because I think there were some studies showing that drinking red wine decreases the risk of heart attack, but then like alcohol increases your risk of hypertension and other things.

00:10:04.195 --> 00:10:06.144
So it's like, it's such a like

00:10:06.294 --> 00:10:06.725
Yeah,

00:10:07.794 --> 00:10:08.225
anyways.

00:10:08.254 --> 00:10:09.414
Um, okay.

00:10:09.414 --> 00:10:12.544
So I want to talk about like what standard drinks are.

00:10:12.544 --> 00:10:14.315
So in the U S.

00:10:14.764 --> 00:10:22.481
Uh, serving of alcohol is five fluid ounces of wine, 12 ounces of beer, or, one and a half ounces of liquor.

00:10:22.735 --> 00:10:23.434
that's a serving

00:10:23.654 --> 00:10:25.325
That's a serving of alcohol.

00:10:25.455 --> 00:10:29.054
But, we have to add to this, that is what beer used to be.

00:10:29.105 --> 00:10:31.865
That was like, our good old Budweiser and such.

00:10:32.053 --> 00:10:32.864
I mean, it still is.

00:10:32.864 --> 00:10:33.823
That's your average beer.

00:10:33.833 --> 00:10:35.293
That's not your craft,

00:10:35.428 --> 00:10:35.899
Right.

00:10:35.994 --> 00:10:37.504
fancy IPA type.

00:10:37.504 --> 00:10:39.014
The thing I

00:10:39.304 --> 00:10:39.985
Yes.

00:10:40.164 --> 00:10:42.158
So, I thought it was four ounces of wine.

00:10:42.158 --> 00:10:42.889
You sure it's five?

00:10:44.303 --> 00:10:44.903
saw was five

00:10:45.139 --> 00:10:45.458
Okay.

00:10:45.673 --> 00:10:46.354
because I just looked it up.

00:10:47.158 --> 00:10:47.568
So,

00:10:47.864 --> 00:10:49.323
Maybe they increased it.

00:10:49.563 --> 00:10:50.053
What's that?

00:10:50.413 --> 00:10:50.913
Maybe they

00:10:51.244 --> 00:10:51.783
Yeah, right?

00:10:51.783 --> 00:10:53.014
The powers that be increased it.

00:10:53.464 --> 00:10:54.573
The wine industry was there.

00:10:54.884 --> 00:10:58.706
Um, the higher the alcohol content, obviously the lower the volume you can do.

00:10:58.706 --> 00:11:02.767
So with beer, if it's a four or 5 percent beer, you can get 12 ounces.

00:11:03.277 --> 00:11:06.937
But if it's a six to 8 percent beer, 12 ounces is going to be

00:11:07.241 --> 00:11:07.591
A lot.

00:11:07.642 --> 00:11:08.091
Yeah.

00:11:08.106 --> 00:11:08.716
than one serving.

00:11:10.042 --> 00:11:10.422
Yeah.

00:11:10.741 --> 00:11:24.705
So, um, the cancers that are implicated in alcohol consumption are breast and it's hormone receptor positive HER2 negative breast is one of them.

00:11:24.705 --> 00:11:33.188
And I think the other one is lobular, colorectal cancer, esophageal cancer, liver, oral cancers.

00:11:33.658 --> 00:11:38.085
Um, and then pharyngeal, your pharynx, laryngeal cancer.

00:11:38.169 --> 00:11:38.389
hmm.

00:11:38.792 --> 00:11:40.341
So, and it doesn't matter what you drink.

00:11:40.341 --> 00:11:43.631
It's not like, oh, well, then I just won't drink liquor, I'll just drink beer.

00:11:43.631 --> 00:11:44.182
It doesn't matter.

00:11:44.182 --> 00:11:45.182
It's alcohol in general.

00:11:45.344 --> 00:11:45.764
Mm hmm.

00:11:45.889 --> 00:11:52.162
and then this is kind of a interesting statistic that for breast cancer itself, 16.

00:11:52.162 --> 00:11:57.572
4 percent of total breast cancer cases are attributable to alcohol.

00:11:57.572 --> 00:11:58.001
Wow.

00:11:58.447 --> 00:11:58.797
Yeah.

00:11:59.011 --> 00:11:59.841
That seems like a lot.

00:12:00.476 --> 00:12:01.126
It does.

00:12:01.470 --> 00:12:02.009
It does.

00:12:02.256 --> 00:12:06.506
you know, we've both had patients who've never had a stitch of alcohol in their life and they've had breast cancer.

00:12:06.506 --> 00:12:08.606
So, you know, it's breast cancer happens.

00:12:08.937 --> 00:12:12.216
But it is it is a big number.

00:12:12.616 --> 00:12:19.106
It seems like, well, it's more than my population, but maybe I don't have the general population coming through my doors when I practice, right?

00:12:19.236 --> 00:12:19.586
So,

00:12:20.006 --> 00:12:20.386
You're right.

00:12:20.386 --> 00:12:31.596
You because because in private practice, you tend to have people who are more naturopathic, perhaps a little bit more mindful of their consumption.

00:12:32.057 --> 00:12:32.417
Yeah.

00:12:32.866 --> 00:12:46.600
Yeah, I do recall that one incidence of a woman who I actually, I was actually a visiting doctor in Indiana at the time when I asked her what she drank, and she said she had a drink every night when she got home, and I said, Oh, what do you drink?

00:12:46.600 --> 00:12:48.250
And she said, I drink whiskey.

00:12:48.470 --> 00:12:49.049
I believe it was whiskey.

00:12:49.049 --> 00:12:49.830
I know it was hard liquor.

00:12:50.480 --> 00:12:52.409
And I said, So you only have one drink?

00:12:52.409 --> 00:12:53.090
She said, Yes.

00:12:53.139 --> 00:12:55.200
And I said, How big is your glass?

00:12:56.039 --> 00:12:57.990
And she's, she kind of smiled wryly.

00:12:57.990 --> 00:13:00.267
She's like, It's a, it's like a highball glass.

00:13:00.277 --> 00:13:01.307
It's probably about four ounces.

00:13:02.200 --> 00:13:02.620
So

00:13:03.059 --> 00:13:05.210
like she's having like, you know, double shot at

00:13:05.279 --> 00:13:07.740
yeah, so all that is is a risk factor.

00:13:07.750 --> 00:13:09.600
It doesn't mean it caused her cancer.

00:13:09.610 --> 00:13:16.320
I, I want to be really careful about that because I think blaming people for their own cancer is a really dangerous place to go.

00:13:16.899 --> 00:13:21.970
But it's no different than any other risk factor for any other condition or something out in the world.

00:13:21.971 --> 00:13:33.330
I mean, it's, it's, You control the risk factors that you can control in your behavior and your lifestyle as best you can, because there are many risk factors you can't control, like your own You know, family history, for example, your genes,

00:13:33.695 --> 00:13:40.544
Or the exposures that we get every single day, you know, from the air and the soil, like we can't control those things.

00:13:40.659 --> 00:13:41.710
right, right.

00:13:41.720 --> 00:13:43.169
So risk factors add up.

00:13:43.169 --> 00:13:57.860
So if somebody is, I don't know, they're sedentary and they are drinking a lot and they end up, um, taking on smoking, I mean, now you're, you're, you're getting an additive effect of risk factors as you pile them on.

00:13:57.870 --> 00:14:11.095
So I want to say that just to be clear that even this woman who I, Had a lot of empathy for because, you know, she didn't know that that was a risk factor for breast cancer until she was told afterwards, and there's no guarantee that was what caused it.

00:14:11.215 --> 00:14:11.745
Could have been something

00:14:11.999 --> 00:14:16.764
No, and I mean, that's where we met was at that cancer center in Indiana.

00:14:17.105 --> 00:14:23.115
And you know, we had a lot of patients who worked in factories and they worked around formaldehyde and all these other chips and chemicals.

00:14:23.115 --> 00:14:25.595
And so it's the compounding of every single thing.

00:14:25.605 --> 00:14:27.914
It's not the one thing.

00:14:28.355 --> 00:14:28.835
Um.

00:14:28.845 --> 00:14:28.865
Yeah.

00:14:29.159 --> 00:14:30.000
So, yeah, for sure.

00:14:30.000 --> 00:14:35.629
So, okay, let's talk about what is it about alcohol that is carcinogenic.

00:14:35.639 --> 00:14:39.350
And the first thing that we always talk about is acetaldehyde.

00:14:39.644 --> 00:14:40.115
Mm hmm.

00:14:41.070 --> 00:14:45.360
And this is a compound that damages DNA

00:14:45.818 --> 00:14:46.389
Directly.

00:14:46.418 --> 00:14:46.859
Yes.

00:14:47.323 --> 00:14:47.774
Yeah.

00:14:47.964 --> 00:14:50.783
So that's kind of like The big one.

00:14:50.854 --> 00:14:52.333
And it's also the hardest one to say.

00:14:53.464 --> 00:14:54.313
had to get that out of the

00:14:54.658 --> 00:14:55.178
Yeah.

00:14:55.259 --> 00:15:02.918
Acetaldehyde is, um, it blocks the repair of the DNA and it also increases inflammation.

00:15:02.999 --> 00:15:05.918
It also increases the inflammatory state within the body.

00:15:05.918 --> 00:15:05.933
Mm hmm.

00:15:06.474 --> 00:15:06.813
Yeah.

00:15:06.813 --> 00:15:09.433
So oxidative stress would be like another cause.

00:15:09.474 --> 00:15:11.394
And so that kind of is a nice segue.

00:15:11.433 --> 00:15:11.953
Good going.

00:15:12.313 --> 00:15:17.443
Um, and so oxidative stress also damages DNA and increases inflammation.

00:15:18.303 --> 00:15:28.087
yeah, the other piece alcohol does directly is it affects our Nitric oxide pathways to create free radicals that way too.

00:15:28.128 --> 00:15:36.280
So nitric oxide is Not good because nitric oxide within the cells and within the nucleus can block DNA repair as well.

00:15:36.860 --> 00:15:38.480
So That's another pathway.

00:15:38.480 --> 00:15:53.783
And the other that I think about, and I don't think it's well established, but it makes perfect sense, is alcohol can lead to a deficiency in certain B vitamins, and it can lead to a deficiency in folic acid, or folate, more, more, um, precisely.

00:15:54.283 --> 00:16:12.298
So folate is needed for normal cells to reproduce in our bodies and we need folate when DNA replicates within our cells within normal cellular repair day to day and so alcohol leading to a deficiency of folate can probably also have an additive effect to the whole carcinogenic process.

00:16:12.658 --> 00:16:12.938
Yeah.

00:16:12.938 --> 00:16:16.874
the other thing is that it affects our hormones.

00:16:17.844 --> 00:16:20.254
So it affects the endocrine system overall.

00:16:20.364 --> 00:16:25.703
So I think in my mind, I always think like, yeah, it can affect, how estrogen and other hormones are metabolized.

00:16:26.014 --> 00:16:34.464
But it affects the entire, hypothalamic axes, like it affects thyroid, um, and, insulin growth factor.

00:16:34.474 --> 00:16:37.998
all of the other, the other hormones in the endocrine system.

00:16:38.331 --> 00:16:42.788
So that's one thing that I don't think a lot of people are aware of.

00:16:43.173 --> 00:16:56.923
And As we've discussed in other episodes, hormones are messengers and so alcohol can change how these chemical messengers are made and how they, um, communicate with each other and that could be like neurotransmitters.

00:16:58.208 --> 00:17:04.128
it can be just, you know, the hormones, estrogen, testosterone, um, progesterone that we think of.

00:17:04.348 --> 00:17:07.318
it's affecting the communication on how our cells talk to each other.

00:17:07.638 --> 00:17:08.118
Mm hmm.

00:17:08.395 --> 00:17:18.820
Yeah, and I think another thing that alcohol does, which is just logical, and I don't know how much research has been done in this so far, it affects the biomes of the body.

00:17:19.115 --> 00:17:21.391
I mean, most bacteria can't live in alcohol.

00:17:22.030 --> 00:17:40.340
And so when you take alcohol down, whether you're affecting your mouth or anywhere along your GI tract, your small intestine, your large intestine, you're probably affecting your microbiome in ways that we're just beginning to understand and we know That that microbiome has a lot to do with our overall health and our immune system And so there's the direct effects.

00:17:40.351 --> 00:17:44.941
I would call that an indirect effect because it probably Adversely affects the populations there.

00:17:45.560 --> 00:17:50.786
That would be my guess Because it's not really considered a healthy thing to be consuming alcohol.

00:17:50.933 --> 00:17:56.364
and, you know, in the research that I did for this, for this episode that nobody mentioned microbiome.

00:17:56.403 --> 00:17:57.193
And so I, I think.

00:17:57.397 --> 00:18:04.788
I think that's a great thing to look at and it is something that we tend to mention at least once every couple of episodes.

00:18:05.758 --> 00:18:06.468
So, Yeah.

00:18:06.468 --> 00:18:18.407
it's, that's a, I mean, that's a really interesting, cause I mean, I, I saw the, you know, about it causing nutrient deficiencies and it being empty calories, but yeah, nothing said directly, you're kind of a solvent.

00:18:19.143 --> 00:18:30.519
yeah You're drinking something bacterial can't live in so that can't be good You're definitely monkeying with your microbiota in unknown ways.

00:18:30.673 --> 00:18:31.983
yeah, yeah.

00:18:32.097 --> 00:18:36.407
So, I mean, do with the information as, as you, as you wish.

00:18:36.718 --> 00:18:44.958
I think just kind of letting more people know when I was reading an article, it said that less than half of Americans knew that alcohol was carcinogenic.

00:18:45.242 --> 00:18:46.143
I saw that

00:18:46.468 --> 00:18:49.488
So I guess not enough people listen to our episode.

00:18:52.218 --> 00:18:55.178
So maybe they'll listen to this one, but, um, yeah.

00:18:55.178 --> 00:19:06.171
And you know, there are options more and more options I'm seeing, at least in Portland area, um, that if you go to a bar restaurant, there are mocktails there.

00:19:06.681 --> 00:19:16.833
We did, I think it was four years ago, we did a post on, different mock tales and, Non or low alcohol products.

00:19:17.282 --> 00:19:21.932
So we'll put a link to that in the show notes and maybe I'll add onto it.

00:19:21.952 --> 00:19:23.722
I'm not going to promise anything cause

00:19:24.038 --> 00:19:26.907
So, so here's a, here's a legitimate question.

00:19:27.008 --> 00:19:29.488
What about cultures who drink every day?

00:19:29.617 --> 00:19:35.411
Like I'm thinking of Italy, go to Italy, people have a glass of wine with lunch and then they go back to work.

00:19:35.461 --> 00:19:38.171
I mean, it's just part of what you do.

00:19:38.385 --> 00:19:39.885
I mean, this is worldwide.

00:19:39.915 --> 00:19:42.605
Obviously this is something that is occurring worldwide.

00:19:42.625 --> 00:19:46.125
I think, there are, I don't think I have my notes in front of me.

00:19:48.596 --> 00:19:54.776
741, 300 cancer cases worldwide can be attributed to, Alcohol.

00:19:54.895 --> 00:19:56.175
And that's from 2020.

00:19:56.455 --> 00:19:57.915
So this is a worldwide problem.

00:19:58.276 --> 00:19:59.306
I don't know.

00:19:59.306 --> 00:20:03.185
And I did not look up specific things with other countries.

00:20:03.653 --> 00:20:10.660
the wines in Italy and I could be wrong, but but it was my impression that they are lower in alcohol.

00:20:11.075 --> 00:20:12.127
Oh yeah.

00:20:12.505 --> 00:20:12.694
yeah.

00:20:12.694 --> 00:20:17.994
And like the ones that, that there are certain ones that people would drink, like during the daytime, the more social wines.

00:20:18.005 --> 00:20:19.375
And it was my understanding.

00:20:19.375 --> 00:20:20.694
Those are lower in alcohol.

00:20:20.934 --> 00:20:23.244
I don't know specifically if that is true.

00:20:23.664 --> 00:20:28.146
you know, like you said, like it's other factors that, you know, in, involved.

00:20:28.146 --> 00:20:31.676
So, and, and it's hard to say because in Europe people smoke a lot.

00:20:31.686 --> 00:20:33.307
So you've got people smoking and drinking alcohol.

00:20:33.567 --> 00:20:35.777
I have no, I have no idea how they do that.

00:20:35.777 --> 00:20:37.727
It's kind of like the French paradox, right?

00:20:38.321 --> 00:20:38.801
Right.

00:20:39.096 --> 00:20:40.547
Throw in some fatty foods.

00:20:40.547 --> 00:20:43.057
And I mean, is it because of the diet that they eat?

00:20:43.086 --> 00:20:48.461
I don't know because American diet versus, you know, uh, Italian diet.

00:20:48.933 --> 00:20:52.223
We eat far more ultra processed foods.

00:20:52.354 --> 00:20:52.933
Um,

00:20:53.058 --> 00:20:53.419
Yeah.

00:20:53.419 --> 00:20:55.118
I couldn't believe the stats around that.

00:20:55.128 --> 00:21:01.028
I recently saw 60 percent of people's calories or something was ultra processed food.

00:21:01.304 --> 00:21:01.624
yeah.

00:21:01.624 --> 00:21:07.403
And we'll go, we'll, we're going to talk about that in another episode and we're going to talk about the difference between processed food and ultra processed food.

00:21:07.743 --> 00:21:13.443
But yeah, so I don't, you know, all of these other factors, is it, do they have less stress in their life?

00:21:13.574 --> 00:21:13.634
Do they

00:21:14.713 --> 00:21:15.243
Right.

00:21:15.263 --> 00:21:15.753
mechanisms?

00:21:15.763 --> 00:21:16.273
Like my,

00:21:16.534 --> 00:21:19.957
Well, it is, their entire food system is different though.

00:21:20.257 --> 00:21:27.946
So I personally think, let's say you're eating all Italian diet here in the United States, sourcing everything from your local grocer here in the U.

00:21:27.946 --> 00:21:33.007
S., it doesn't seem as healthy as Italy because of our mass production of everything.

00:21:33.176 --> 00:21:39.807
Because we pick the tomato when it's green and then we throw some chemical on it to make it red just before it's at the shelves.

00:21:40.017 --> 00:21:43.747
We put it in a gigantic you know, 18 Wheeler, ship it across the country.

00:21:43.757 --> 00:21:44.856
It's just so different.

00:21:44.866 --> 00:21:48.411
Like our food systems don't serve us.

00:21:48.441 --> 00:21:51.461
I mean, unless you have local growers and you can constantly go to the market.

00:21:51.800 --> 00:21:56.641
I mean, it's, it's hard here to mimic exactly the, the, the diet they have there.

00:21:56.651 --> 00:21:57.530
Even the oils.

00:21:57.530 --> 00:22:09.727
Like I was in Italy last spring, every restaurant we went to had its own olive oil from their own little small olive grower down the road, and we were not going to fancy restaurants.

00:22:10.021 --> 00:22:18.298
These were just regular restaurants, some of them very touristy, but it was just a different way of obtaining your food.

00:22:18.398 --> 00:22:23.955
And here, we just have agribusiness, and I think that that's a huge problem.

00:22:24.546 --> 00:22:30.155
Do they, and now we're going into like more like tourism conversations, but it's my dream to go to Italy.

00:22:30.405 --> 00:22:32.546
Do they kind of linger over their meals?

00:22:32.546 --> 00:22:45.778
Like in Spain, like in Spain, I remember, it's not like, Standing over the stove and shoveling food in your mouth or quickly eating at the table and then clearing the plates like it's seems like it's a much more relaxed, almost like type of thing.

00:22:46.248 --> 00:22:46.938
I would agree.

00:22:46.938 --> 00:22:52.228
I think the food is almost incidental to the convivial company you're keeping during the meal.

00:22:52.397 --> 00:22:57.928
So, the food happens, but the bulk of what's happening is the interaction of the people at the table.

00:22:58.188 --> 00:23:12.448
And, of course, you're doing it over food, but Yes, it's a very different experience where the conviviality and the food seem to be on par rather than I'm sitting down to eat, they're sitting down to visit and they're eating while they visit.

00:23:13.258 --> 00:23:13.657
Well, yeah.

00:23:13.657 --> 00:23:17.431
And again, this, this is a worldwide concern.

00:23:17.490 --> 00:23:23.441
And so I don't know the specifics on, um, the statistics from other, other countries.

00:23:23.451 --> 00:23:26.181
So, I mean, it is something interesting for us to look into.

00:23:26.290 --> 00:23:40.924
I do know that the Mediterranean diet does lead to greater longevity in general, whether we're talking about Greece or Spain or Italy so we do know that eating a lot of plant foods, maybe that somehow negates some of the alcohol carcinogenesis too, because we're talking about oxidative damage.

00:23:41.349 --> 00:23:41.930
Right.

00:23:42.720 --> 00:23:43.849
Colorful foods.

00:23:43.900 --> 00:23:44.359
Right.

00:23:44.380 --> 00:23:49.019
And then also you were talking about, you know, it's, it's very social.

00:23:49.029 --> 00:23:53.150
There's like a sense of community, which I think we're really lacking in the U.

00:23:53.150 --> 00:23:53.589
S.

00:23:53.650 --> 00:23:57.640
And so, I mean, who knows, we're at this point, we're just, we're spitballing.

00:23:58.009 --> 00:23:59.730
But I think these are things to consider.

00:23:59.914 --> 00:24:00.825
Yeah, for sure.

00:24:00.825 --> 00:24:06.704
I mean, it's, it's clear that some of our habits here in America are not good for our health and, uh, isolation.

00:24:07.009 --> 00:24:07.609
alcohol.

00:24:07.609 --> 00:24:08.140
They're just not.

00:24:08.265 --> 00:24:10.075
isolation is definitely high on that list.

00:24:10.190 --> 00:24:10.640
Yeah.

00:24:10.700 --> 00:24:17.246
So, yeah, typically we talk about things that you can do to decrease your risk and

00:24:17.605 --> 00:24:19.394
Can I highly recommend the mocktails?

00:24:19.755 --> 00:24:21.875
The recipes you put on the blog that you already mentioned.

00:24:22.150 --> 00:24:22.559
Yes.

00:24:22.644 --> 00:24:26.134
I highly recommend trying to make some mocktails at home if a cocktail is your thing.

00:24:26.518 --> 00:24:30.337
I think kombucha in a glass, put a wine glass, but you pour your kombucha in there.

00:24:30.718 --> 00:24:34.448
I think that's a nice way to, like, feel like you're doing something that's alcoholic, but you're not.

00:24:34.448 --> 00:24:34.587
Yeah.

00:24:35.192 --> 00:24:40.742
that is and I actually drink kombucha from we have these like glasses that look like cans.

00:24:40.742 --> 00:24:42.343
They're kind of can shape of their glasses.

00:24:42.343 --> 00:24:43.573
And that's how I drink my kombucha.

00:24:43.701 --> 00:24:44.010
yeah,

00:24:44.119 --> 00:24:46.829
And we're sometimes I drink it out of a highball class.

00:24:47.734 --> 00:24:48.315
yeah,

00:24:48.839 --> 00:24:50.269
And I'm not saying I don't drink alcohol.

00:24:50.269 --> 00:24:51.089
I do drink alcohol.

00:24:51.089 --> 00:24:51.970
I try to limit it.

00:24:52.019 --> 00:24:55.846
Like if I go out, you know, one drink, not perfect.

00:24:56.415 --> 00:24:58.823
Um, but, um, And I don't go out a lot.

00:24:58.833 --> 00:25:04.913
And I think that's when I go out, if I go out, but, um, yeah.

00:25:04.913 --> 00:25:20.863
And I do have a habit of, if I go out, I tend to, if they have fries, I'll have fries and that's probably a really bad thing to have, you know, that's, that's not really as good as a, as I think it is.

00:25:21.163 --> 00:25:24.910
So, yeah, just being mindful of risk factors in your life.

00:25:24.910 --> 00:25:25.829
I think that's kind of what you're

00:25:25.964 --> 00:25:29.275
And we didn't really mention this, but there is a linear relationship.

00:25:29.275 --> 00:25:36.454
So it's If one drink is bad, two drinks is worse, three drinks is worse, four drinks is worse, as far as risk goes.

00:25:36.464 --> 00:25:42.625
So we know that people who drink heavily have a much, much higher risk, you know, four drinks a day or more.

00:25:43.144 --> 00:25:45.244
And, and that goes on occasion too.

00:25:45.244 --> 00:25:49.964
Like you shouldn't really over drink to the point of getting drunk or buzzed.

00:25:50.201 --> 00:26:01.746
that's when you know that it's toxic to your brain as well, for sure, because that's why it is intoxication, toxic, So it's toxic to your brain at that moment.

00:26:01.746 --> 00:26:02.556
It's easy to remember.

00:26:02.925 --> 00:26:03.746
I didn't make that up.

00:26:03.746 --> 00:26:07.855
Some smart neurologist in the integrative space said it and I was like, Oh, that's a really good point.

00:26:08.385 --> 00:26:13.736
Um, so yeah, so if you're going to drink, don't over drink.

00:26:14.115 --> 00:26:19.066
because I think you've passed the point of any benefit if there is any, whether it's for your heart or your brain or anything else.

00:26:19.363 --> 00:26:20.363
I think that's good advice.

00:26:22.032 --> 00:26:23.282
I like to do some absolute.

00:26:23.393 --> 00:26:24.972
It's not even in moderation.

00:26:24.972 --> 00:26:26.163
It's less than moderation.

00:26:26.182 --> 00:26:31.054
It's, you know, disperse your alcohol with a club soda.

00:26:31.074 --> 00:26:33.104
Like, I think having that same feel.

00:26:33.104 --> 00:26:34.913
And that was the thing when I was making mocktails.

00:26:34.973 --> 00:26:35.683
Disperse?

00:26:36.034 --> 00:26:36.864
You know what I'm trying to say.

00:26:37.193 --> 00:26:40.923
But, you know, like inter intermix.

00:26:40.923 --> 00:26:52.767
And so if you have something that also has bubbles, like a kombucha or like a club soda with lime or twist or, you know, a splash of juice or something like that's that mouthfeel.

00:26:52.807 --> 00:26:56.326
And that's what's really hard to replicate with, um, with mocktails.

00:26:56.346 --> 00:26:59.797
But, um, yeah, putting a little citrus in there, putting a little bubble.

00:27:00.136 --> 00:27:00.636
Mm hmm.

00:27:00.846 --> 00:27:01.257
Mm hmm.

00:27:01.356 --> 00:27:02.686
I, I totally agree.

00:27:02.807 --> 00:27:06.047
Or just using some bitters with the bubbly water.

00:27:06.136 --> 00:27:18.017
Makes you think you have a cocktail because there's kind of that, another flavor and there's all sorts of bitters out there now, not just Angostura, but there's all sorts of nice bitters available in the liquor stores or grocery stores, depending what state you're in.

00:27:18.376 --> 00:27:25.626
Or the Portland Airport PDX, they've got, they've got the place that sells whiskey and they've got a bunch of different bitters there.

00:27:25.836 --> 00:27:32.287
And yeah, I mean, if you're, you know, having that small amount, I mean, there's, it's a very, very small amount of alcohol that would be in bitters

00:27:32.324 --> 00:27:32.713
Yeah.

00:27:32.713 --> 00:27:33.743
I don't think there's much in there.

00:27:34.763 --> 00:27:35.878
It's almost like a tincture.

00:27:36.124 --> 00:27:37.034
you only use drops.

00:27:37.673 --> 00:27:41.993
Yeah, Yeah, So, unlike a tincture, which I dose in teaspoons for some people.

00:27:42.223 --> 00:27:44.003
I mean, bitters is less than that.

00:27:44.578 --> 00:27:45.058
Yeah.

00:27:45.419 --> 00:27:47.838
I wonder how much alcohol's in a serving of NyQuil.

00:27:48.148 --> 00:27:52.538
Okay, those are questions that we're going to answer at some other time.

00:27:52.538 --> 00:27:53.449
Because I think this is it.

00:27:53.489 --> 00:27:54.439
I think we've covered it.

00:27:54.459 --> 00:27:59.878
I think, this is a good recap of episode four for those who did not listen to us at that time.

00:28:00.304 --> 00:28:01.124
It's still online.

00:28:01.173 --> 00:28:03.604
It's still in your podcast player.

00:28:04.269 --> 00:28:07.019
Yeah, so, so see how we were getting around.

00:28:07.219 --> 00:28:08.388
I was really afraid.

00:28:08.398 --> 00:28:13.885
That episode really, I remember starting off and being really afraid that it was just going to like piss people off.

00:28:13.925 --> 00:28:14.736
But, you know, now

00:28:14.760 --> 00:28:14.840
I know.

00:28:14.965 --> 00:28:15.955
the Surgeon General behind

00:28:16.131 --> 00:28:16.510
Yeah.

00:28:16.767 --> 00:28:17.136
Yeah.

00:28:17.391 --> 00:28:18.510
Don't blame the messenger.

00:28:19.050 --> 00:28:19.911
We didn't make the data.

00:28:20.326 --> 00:28:22.356
We both have cocktails on occasion, too.

00:28:22.547 --> 00:28:24.836
So, like you said, there's nothing wrong with that.

00:28:24.846 --> 00:28:24.926
It's

00:28:25.153 --> 00:28:27.101
We all have one.

00:28:27.101 --> 00:28:27.586
Together.

00:28:27.586 --> 00:28:28.817
together on occasion.

00:28:29.757 --> 00:28:30.457
It's okay.

00:28:30.916 --> 00:28:33.606
We're, we're mindful of the risk we're taking at that moment.

00:28:34.057 --> 00:28:35.416
Cause that's what you get to do as an adult.

00:28:35.740 --> 00:28:36.980
so on that note, I'm Dr.

00:28:36.980 --> 00:28:37.770
Leah Sherman,

00:28:37.951 --> 00:28:39.181
Kazer.

00:28:39.381 --> 00:28:40.681
and this is The Cancer Pod.

00:28:40.800 --> 00:28:41.510
Until next time.

00:28:41.653 --> 00:28:43.394
Thanks for listening to the cancer pod.

00:28:43.753 --> 00:28:48.253
Remember to subscribe, review and rate us wherever you get your podcasts.

00:28:48.854 --> 00:28:53.804
Follow us on social media for updates, and as always, this is not medical advice.

00:28:54.104 --> 00:28:55.574
These are our opinions.

00:28:55.993 --> 00:28:59.144
Talk to your doctor, but for changing anything related to your treatment plan.

00:28:59.647 --> 00:29:01.657
The cancer pod is hosted by me, Dr.

00:29:01.657 --> 00:29:02.438
Leah Sherman.

00:29:02.738 --> 00:29:03.337
And by Dr.

00:29:03.337 --> 00:29:08.048
Tina Kaczor music is by Kevin See you next time.